40787-96-0

Usage

Uses

Used in Pharmaceutical Industry:
3-Bromo-4-nitroaniline is used as a chemical intermediate for the synthesis of pharmaceuticals, contributing to the development of new drugs and medicinal compounds. Its reactivity allows for the creation of a variety of derivative compounds that can possess therapeutic properties.
Used in Dye Industry:
In the dye industry, 3-Bromo-4-nitroaniline serves as a precursor for the production of various dyes. Its chemical structure lends itself to the formation of colored compounds, making it a valuable component in the creation of a range of dye products.

InChI:InChI=1/C6H5BrN2O2/c7-5-3-4(8)1-2-6(5)9(10)11/h1-3H,8H2

Upstream product

• 621-38-5 3-bromoacetanilide 
• 591-19-5 m-Bromoaniline 
• 577-19-5 2-nitrophenyl bromide 
• 7664-93-9 sulfuric acid 
• 64-19-7 acetic acid 
• 19230-47-8 3-bromo-4-nitroacetanilide 

Downstream Products

• 27721-82-0 3-bromo-4-nitro-1,1'-biphenyl 
• 577-19-5 2-nitrophenyl bromide 
• 51686-78-3 2,4-dibromonitrobenzene 
• 102000-73-7 3-bromo-4-nitrobenzonitrile 
• 860603-83-4 2-bromo-4-iodo-1-nitro-benzene 
• 5540-59-0 Nonanoic acid (3-bromo-4-nitro-phenyl)-amide 
• 158531-07-8 3-bromo-4-nitro-N-<<2-(trimethylsilyl)ethyl>sulfonyl>aniline 
• 1380445-44-2 tert-butyl N-(3-bromo-4-nitrophenyl)carbamate 
• 1126651-91-9 (2,5-diaminophenyl)-phosphonic acid diethyl ester 
• 108013-74-7 N-(2-Nitro-5-carboxy-phenyl)-DL-α-alanin-diaethylester 
• 103041-12-9 N-(2-Nitro-5-carboxy-phenyl)-DL-α-alanin 
• 24339-60-4 1,2,3,4-tetrabromo-5-nitrobenzene 
• 101420-81-9 3-Bromo-4-nitrobenzoic acid 
• 158531-06-7 N-<2-nitro-5-<<(trimethylsilyl)sulfonyl>amino>phenyl>phthalimide 

Relevant academic research and scientific papers

Synthesis of symmetric dinitro-functionalised troeger's base analogues

The synthesis of six new examples of 2,8-dinitro-substituted Troeger's base analogues are reported, together with the first examples of 1,7-, 3,9- and 4,10-dinitro Troeger's base analogues and the first example of a tetranitro Troeger's base compound. Several of these dinitro compounds lack substituents at the 2- and 8-positions and therefore provide further examples of Troeger's base analogues derived from anilines lacking a para substituent.

Nitroarylamines via the Vicarious Nucleophilic Substitution of Hydrogen: Amination, Alkylamination, and Arylamination of Nitroarenes with Sulfenamides

A new reaction of sulfenamides with electrophilic arenes under basic conditions is described. The σ adducts formed from nitroarenes and the anions of sulfenamides undergo elimination of thiol to produce the corresponding o- and/or p-nitroanilines. This reaction is analogous to the known alkylation and hydroxylation of nitroarenes via the vicarious nucleophilic substitution of hydrogen (VNS). The reaction gives access to a wide range of substituted nitroanilines, nitronaphthylamines, and aminoheterocycles. By means of the reaction with N-alkyl- and N-arylsulfenamides, it is possible to obtain N-alkylnitroanilines and nitrodiarylamines. By varying the structure of sulfenamide and the reaction conditions, particularly the nature and concentration of the base, it is possible to control the orientation of animation.