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2-methyl-4-(4-trifluoromethyl-benzylidene)-4H-oxazol-5-one is a complex organic compound with the molecular formula C12H8F3NO2. It features a 4H-oxazol-5-one core structure, which is a heterocyclic ring system containing oxygen and nitrogen atoms. The compound is characterized by a methyl group at the 2-position and a 4-trifluoromethyl-benzylidene group at the 4-position, which is a benzylidene moiety with a trifluoromethyl substituent. This chemical structure may be of interest in various fields, such as pharmaceuticals or materials science, due to its potential applications in the development of new drugs or chemical compounds. The specific properties and reactivity of 2-methyl-4-(4-trifluoromethyl-benzylidene)-4H-oxazol-5-one would depend on its molecular structure and the electronic effects of the trifluoromethyl group, which can influence its stability, solubility, and potential interactions with other molecules.

4083-33-4

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4083-33-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4083-33-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,0,8 and 3 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4083-33:
(6*4)+(5*0)+(4*8)+(3*3)+(2*3)+(1*3)=74
74 % 10 = 4
So 4083-33-4 is a valid CAS Registry Number.

4083-33-4Relevant academic research and scientific papers

5-Benzylidene-4-oxazolidinones potently inhibit biofilm formation in Methicillin-resistant Staphylococcus aureus

Edwards, Grant A.,Shymanska, Nataliia V.,Pierce, Joshua G.

supporting information, p. 7353 - 7356 (2017/07/11)

Investigation into the biological function of 5-benzylidene-4-oxazolidinones revealed dose-dependent inhibition of biofilm formation in Methicillin-resistant S. aureus (MRSA). This structurally unusual class of small molecules inhibit up to 89% of biofilm formation with IC50 values as low as 0.78 μM, and disperse pre-formed biofilms with IC50 values as low as 4.7 μM. Together, these results suggest that 4-oxazolidinones represent new chemotypes to enable the study of bacterial biofilms with small molecule chemical probes.

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