40832-73-3

Basic information

• Product Name: Piperidine, 1-(4-chlorophenyl)-
• CAS NO: 40832-73-3
• Molecular Formula: C11H14ClN
• Molecular Weight: 195.692
• Mol File: 40832-73-3.mol
• Article Data: 31

Chemical Properties

• CAS DataBase Reference: Piperidine, 1-(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 1-(4-chlorophenyl)-(40832-73-3)
• EPA Substance Registry System: Piperidine, 1-(4-chlorophenyl)-(40832-73-3)

Safety Data

• Hazardous Substances Data: 40832-73-3(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 106-39-8 bromochlorobenzene 
• 637-87-6 1-Chloro-4-iodobenzene 
• 111-24-0 1,5-dibromo-pentane 
• 698-69-1 4-chloro-N,N-dimethylaniline 
• 106-46-7 para-dichlorobenzene 
• 21700-74-3 (p-chlorophenyl)triethoxysilane 
• 110210-11-2 1-(2,4-dinitrophenoxy)piperidine 
• 132606-28-1 1,1-bis(hydroperoxy)cyclopentane 
• 106-47-8 4-chloro-aniline 
• 111-30-8 Glutaraldehyde 
• 16623-96-4 (cyclododecylidene)bishydroperoxide 
• 2699-11-8 1,1-dihydroperoxycyclohexane 
• 2156-71-0 N-chloropiperidine 

Downstream Products

• 1221276-48-7 C₁₉H₁₉ClN₂O₂ 
• 1221276-65-8 C₁₉H₁₉ClN₂O₃ 
• 1415461-01-6 1-(5-chloro-2-(piperidin-1-yl)phenyl)naphthalen-2-ol 
• 7661-33-8 1-(4-chlorophenyl)pyrrolidin-2-one 
• 1204-85-9 4-(piperidin-1-yl)benzonitrile 

Relevant articles and documents

N-heterocyclic carbene-Pd(II)-2-methyl-4,5-dihydrooxazole complex-catalyzed highly chemoselective mono-amination of dichlorobenzenes

The palladium-catalyzed chemoselective mono-amination of dichlorobenzenes was reported in this paper. Under the suitable conditions, all reactions involving the three isomers of dichlorobenzenes with various secondary and primary amines in the presence of

Electron Donor-Acceptor Complex-Initiated Photochemical Cyanation for the Preparation of α-Amino Nitriles

An electron donor-acceptor complex-initiated α-cyanation of tertiary amines has been described. The reaction protocol provides a novel method to synthesize various α-amino nitriles under mild conditions. The reaction can proceed smoothly without the presence of photocatalysts and transition metal catalysts, and either oxidants are unnecessary or O2 is the only oxidant. The practicality of this method is showcased not only by the late-stage functionalization of natural alkaloid derivatives and pharmaceutical intermediate, but also by the applicability of a stop-flow microtubing reactor.

Practical and regioselective amination of arenes using alkyl amines

The formation of carbon–nitrogen bonds for the preparation of aromatic amines is among the top five reactions carried out globally for the production of high-value materials, ranging from from bulk chemicals to pharmaceuticals and polymers. As a result of this ubiquity and diversity, methods for their preparation impact the full spectrum of chemical syntheses in academia and industry. In general, these molecules are assembled through the stepwise introduction of a reactivity handle in place of an aromatic C–H bond (that is, a nitro group, halogen or boronic acid) and a subsequent functionalization or cross-coupling. Here we show that aromatic amines can be constructed by direct reaction of arenes and alkyl amines using photocatalysis, without the need for pre-functionalization. The process enables the easy preparation of advanced building blocks, tolerates a broad range of functionalities, and multigram scale can be achieved via a batch-to-flow protocol. The merit of this strategy as a late-stage functionalization platform has been demonstrated by the modification of several drugs, agrochemicals, peptides, chiral catalysts, polymers and organometallic complexes.