40893-37-6Relevant academic research and scientific papers
Unexpectedly high activity of Zn(OTf)2·6H2O in catalytic Friedel-Crafts acylation reaction
He, Fei,Wu, Huayue,Chen, Jiuxi,Su, Weike
, p. 255 - 264 (2008)
Zn(OTf)2·6H2O was used to promote Friedel-Crafts acylation of aromatics. The work describes the high activity and efficiency of Zn(OTf)2·6H2O in acylation of aromatics, and the catalyst has surpassed most metal triflates in dispensing when dried at high temperature under vacuum before use. Copyright Taylor & Francis Group, LLC.
Light-Driven Enantioselective Organocatalytic β-Benzylation of Enals
Dell'Amico, Luca,Fernández-Alvarez, Victor M.,Maseras, Feliu,Melchiorre, Paolo
supporting information, p. 3304 - 3308 (2017/03/17)
A photochemical organocatalytic strategy for the direct enantioselective β-benzylation of α,β-unsaturated aldehydes is reported. The chemistry capitalizes upon the light-triggered enolization of 2-alkyl-benzophenones to afford hydroxy-o-quinodinomethanes. These fleeting intermediates are stereoselectively intercepted by chiral iminium ions, transiently formed upon condensation of a secondary amine catalyst with enals. Density functional theory (DFT) studies provided an explanation for why the reaction proceeds through an unconventional Michael-type addition manifold, instead of a classical cycloaddition mechanism and subsequent ring-opening.
Light-Driven Carboxylation of o-Alkylphenyl Ketones with CO2
Masuda, Yusuke,Ishida, Naoki,Murakami, Masahiro
supporting information, p. 14063 - 14066 (2015/11/25)
o-Alkylphenyl ketones undergo a C-C bond forming carboxylation reaction with CO2 simply upon irradiation with UV light or even solar light. The reaction presents a clean process exploiting light energy as the driving force for carboxylation of organic molecules with CO2.
Catalytic Friedel-Crafts acylation of aromatic ethers using Sml3
Chen, Xiaohang,Yu, Mingxin,Wang, Meijun
, p. 80 - 81 (2007/10/03)
10% mol Sml3 catalysed the Friedel-Crafts acylation of aromatic ethers by acyl chlorides in acetonitrile with the yields of 48-82%. Reactions of various substituted aromatic ethers with acyl chloride were studied. The structures of compounds were established by IR and 1H NMR. The main product obtained with anisole is the para-substituted compound with only a trace (3, a pattern repeated with the other aromatic ethers used.
