409060-10-2

Upstream product

• 64-18-6 formic acid 
• 167281-71-2 1-benzoyl-2-(α-benzoyl-β-benzoyloxy-β-phenylvinyl)-1H-benzimidazole 
• 66838-69-5 2-phenacyl-1H-benzimidazole 

Downstream Products

• 409060-11-3 C₁₆H₁₂N₄*ClH 
• 409060-09-9 2-[1-(4-nitrophenyl)-5-phenyl-4-pyrazolyl]-1H-benzimidazole 
• 409060-08-8 2-(1,5-diphenyl-4-pyrazolyl)-1H-benzimidazole 

Relevant academic research and scientific papers

Formation of unsymmetrical 2-(diacylmethylene)-2,3-dihydro-1H-benzimidazoles during acidolysis of 1-benzoyl-2-(β-benzoyloxy-β-phenylvinyl)-1H-benzimidazole

The reaction of 1-benzoyl-2-(β-benzoyloxy-β-phenylvinyl)-1H-benzimidazole with carboxylic acids was investigated. A convenient method was developed for the synthesis of unsymmetrical 2-(diacylmethylene)-2,3-dihydro-1H-benzimidazoles. 2-(4-Pyrazolyl)-1H-benzimidazoles were obtained by the reaction of 2-(benzoylformylmethylene)-2,3-dihydro-1H-benzimidazole with hydrazine.

Synthesis and tautomerism of 2-[3(5)-aryl(methyl)pyrazol-4-yl]-1- benzimidazoles

An efficient method has been developed for the synthesis of 2-[3(5)-aryl(methyl)pyrazol-4-yl]-1H-benzimidazoles by cyclocondensation of 2-acylmethyl-1H-benzimidazoles benzoylhydrazones with DMF dimethylacetal. The tautomerism of the compounds obtained via migrations of a proton between the pyrazole nitrogen atoms has been studied by 1H NMR. The more stable tautomers have electron acceptor aryl substituents placed at position 3 of the pyrazole ring and electron donor aryl substituents or a methyl at position 5. Springer Science+Business Media, Inc. 2006.