40925-62-0

Usage

Physical form

white to light yellow crystalline powder

Use

fluorescent brightening agent in manufacturing of plastics, fibers, and coatings

Potential application

photo-sensitive material in organic electronics

Biological activities

potential anti-tumor and anti-inflammatory properties

Safety

handle with care to avoid harmful effects

Upstream product

• 445-83-0 4-fluoro-1-methoxy-2-nitrobenzene 
• 52177-62-5 3-methoxyphenyl carbonochloridate 
• 150-19-6 O-methylresorcine 
• 3147-64-6 2-hydroxy-6-methoxybenzoic acid 
• 1978-39-8 5-fluoro-2-methoxy-aniline 
• 394-33-2 2-nitro-4-fluorophenol 
• 57-13-6 urea 
• 124782-67-8 2-(N-tert-butoxycarbonylamino)-4-fluoroanisole 

Downstream Products

• 40925-69-7 2-amino-3-methoxyphenol 

Relevant academic research and scientific papers

Versatile Cp*Co(III)(LX) Catalyst System for Selective Intramolecular C-H Amidation Reactions

Herein, we report the development of a tailored cobalt catalyst system of Cp*Co(III)(LX) toward intramolecular C-H nitrene insertion of azidoformates to afford cyclic carbamates. The cobalt complexes were easy to prepare and bench-stable, thus offering a convenient reaction protocol. The catalytic reactivity was significantly improved by the electronic tuning of the bidentate LX ligands, and the observed regioselectivity was rationalized by the conformational analysis and DFT calculations of the transition states. The superior performance of the newly developed cobalt catalyst system could be broadly applied to both C(sp2)-H and C(sp3)-H carbamation reactions under mild conditions.

BENZOXAZINE DERIVATIVES AND USES THEREOF

Compounds of formula (I) or pharmaceutically acceptable salts thereof are provided, wherein each of Z, X, R1, R2, R3, R4, y, n, and Ar are as defined, and described in classes and subclasses herein, which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. The compounds, and compositions thereof, are useful for treating a variety of central nervous system disorders such as schizophrenia.

Benzimidazolidinone derivatives as muscarinic agents

Benzimidazolidinone derivative compounds, which increase acetylcholine signaling or effect in the brain, and highly selective muscarinic agonists, particularly for the M1 and/or M4 receptor subtypes, pharmaceutical compositions comprising the same, as well as methods of treating psychosis using these compounds are disclosed.

Benzimidazolidinone derivatives as muscarinic agents

Benzimidazolidinone derivative compounds, which increase acetylcholine signaling or effect in the brain, and highly selective muscarinic agonists, particularly for the M1 and/or M4 receptor subtypes, pharmaceutical compositions comprising the same, as well as methods of treating psychosis using these compounds are disclosed.

Benzimidazolidinone derivatives as muscarinic agents

Benzimidazolidinone derivative compounds, which increase acetylcholine signaling or effect in the brain, and highly selective muscarinic agonists, particularly for the M1 and/or M4 receptor subtypes, pharmaceutical compositions comprising the same, as well as methods of treating psychosis using these compounds are disclosed.

REGIOSPECIFIC SYNTHESIS OF CERTAIN 1,2,3,4-TETRASUBSTITUTED BENZENES IN ONE STEP VIA A BENZENE CYCLIZATION

Tetrasubstituted benzenes of type 3 are obtained regiospecifically in a single step by the treatment of 1-fluoro-4-methoxy-5-carbo-tert-butoxy aniline with tert-butyllithium followed by reaction with an elecrophile.