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1978-39-8

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1978-39-8 Usage

Uses

5-Fluoro-2-methoxyaniline was used in the study of structure-activity relationship to discover selective inhibitors of p97 ATPase.

Check Digit Verification of cas no

The CAS Registry Mumber 1978-39-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,7 and 8 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1978-39:
(6*1)+(5*9)+(4*7)+(3*8)+(2*3)+(1*9)=118
118 % 10 = 8
So 1978-39-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H8FNO/c1-10-7-3-2-5(8)4-6(7)9/h2-4H,9H2,1H3

1978-39-8 Well-known Company Product Price

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  • Alfa Aesar

  • (H32525)  5-Fluoro-2-methoxyaniline, 97%   

  • 1978-39-8

  • 250mg

  • 400.0CNY

  • Detail
  • Alfa Aesar

  • (H32525)  5-Fluoro-2-methoxyaniline, 97%   

  • 1978-39-8

  • 1g

  • 789.0CNY

  • Detail

1978-39-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Fluoro-2-methoxyaniline

1.2 Other means of identification

Product number -
Other names 5-Fluoro-2-Methoxyaniline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1978-39-8 SDS

1978-39-8Relevant articles and documents

Nucleophilic aromatic substitution of unactivated fluoroarenes enabled by organic photoredox catalysis

Nicewicz, David A.,Pistritto, Vincent A.,Schutzbach-Horton, Megan E.

supporting information, p. 17187 - 17194 (2020/11/02)

Nucleophilic aromatic substitution (SNAr) is a classical reaction with well-known reactivity toward electron-poor fluoroarenes. However, electron-neutral and electron-rich fluoro(hetero)arenes are considerably underrepresented. Herein, we present a method for the nucleophilic defluorination of unactivated fluoroarenes enabled by cation radical-accelerated nucleophilic aromatic substitution. The use of organic photoredox catalysis renders this method operationally simple under mild conditions and is amenable to various nucleophile classes, including azoles, amines, and carboxylic acids. Select fluorinated heterocycles can be functionalized using this method. In addition, the late-stage functionalization of pharmaceuticals is also presented. Computational studies demonstrate that the site selectivity of the reaction is dictated by arene electronics.

Assembly of Primary (Hetero)Arylamines via CuI/Oxalic Diamide-Catalyzed Coupling of Aryl Chlorides and Ammonia

Fan, Mengyang,Zhou, Wei,Jiang, Yongwen,Ma, Dawei

supporting information, p. 5934 - 5937 (2015/12/11)

A general and practical catalytic system for aryl amination of aryl chlorides with aqueous or gaseous ammonia has been developed, with CuI as the catalyst and bisaryl oxalic diamides as the ligands. The reaction proceeds at 105-120°C to provide a diverse set of primary (hetero)aryl amines in high yields with various functional groups.

Synthesis of the marine sponge derived β2-adrenoceptor agonist S1319

Fairhurst, Robin A.,Janus, Diana,Lawrence, Annabel

, p. 4697 - 4700 (2007/10/03)

(Chemical Equation Presented) The marine sponge derived β2-adrenoceptor agonist S1319 has been synthesized following a six-step linear sequence. Central to the approach employed is the formation of a 7-lithiated-2,4-dialkoxybenzothiazole interm

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