40939-34-2Relevant academic research and scientific papers
Cs2CO3-promoted cross-dehydrogenative coupling of thiophenols with active methylene compounds
Chen, Qian,Wang, Xiaofeng,Wen, Chunxiao,Huang, Yulin,Yan, Xinxing,Zeng, Jiekun
, p. 39758 - 39761 (2017)
A convenient and efficient α-sulfenylation of carbonyl compounds has been achieved via the halogen-free Cs2CO3-promoted cross-dehydrogenative coupling (CDC) of thiophenols with active methylene compounds using air as the oxidant unde
Identification of 6-hydroxy-5-phenyl sulfonylpyrimidin-4(1H)-one APJ receptor agonists
Bostwick, Jeffrey S.,Finlay, Heather J.,Galella, Michael A.,Gargalovic, Peter S.,Generaux, Claudia,He, Yan,Jiang, Ji,Luk, Chiuwa E.,Onorato, Joelle M.,Tora, George,Wang, Tao,Wexler, Ruth R.,Xu, Carrie
supporting information, (2021/09/08)
Heart failure (HF) treatment remains a critical unmet medical need. Studies in normal healthy volunteers and HF patients have shown that [Pyr1]apelin-13, the endogenous ligand for the APJ receptor, improves cardiac function. However, the short
Α - sulfinyl carbonyl compound as well as synthesis method and application thereof
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Paragraph 0065-0066, (2019/08/16)
The invention discloses an alpha-sulfenylated carbonyl compound and a synthesis method and application thereof. The synthesis method comprises the following steps: dissolving a beta-dicarbonyl compound and thiophenol by using a solvent, and under the acti
6-HYDROXY-5-(PHENYL/HETEROARYLSULFONYL)PYRIMIDIN-4(1H)-ONE AS APJ AGONISTS
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Page/Page column 84, (2018/01/20)
The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.
