41049-47-2

Basic information

• Product Name: Acetic acid, trifluoro-, 2-iodocyclohexyl ester, trans-
• CAS NO: 41049-47-2
• Molecular Formula: C8H10F3IO2
• Molecular Weight: 322.066
• Mol File: 41049-47-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Acetic acid, trifluoro-, 2-iodocyclohexyl ester, trans-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, trifluoro-, 2-iodocyclohexyl ester, trans-(41049-47-2)
• EPA Substance Registry System: Acetic acid, trifluoro-, 2-iodocyclohexyl ester, trans-(41049-47-2)

Safety Data

• Hazardous Substances Data: 41049-47-2(Hazardous Substances Data)

Upstream product

• 626-62-0 Cyclohexyl iodide 
• 2712-78-9 bis-[(trifluoroacetoxy)iodo]benzene 
• 407-25-0 trifluoroacetic anhydride 
• 110-83-8 cyclohexene 
• 13257-51-7 mercury(II) trifluoroacetate 
• 108164-34-7 C₇H₇F₆IO₄ 
• 131846-61-2 1-(2-iodo-1-trifluoroacetoxy-ethyl)-benzene 
• 2923-19-5 thallium(I) trifluoroacetate 
• 14353-86-7 iodine tris(trifluoroacetate) 
• 34701-03-6 trans-1-bromo-2-iodocyclohexane 

Downstream Products

• 43123-07-5 cis-2-hydroxycyclohexyl 2,2,2-trifluoroacetate 
• 1792-81-0 cis-1,2-cyclohexane 
• 41049-51-8 cis-1,2-cyclohexylene bis(trifluoroacetate) 

Relevant articles and documents

OXIDATION OF ALKENES BY THE Pb(IV)-I2-CF3COOH SYSTEM

The Pb(OAc)4-I2-CF3COOH oxidizing system was discovered, and its reactions with alkenes (cyclohexene, 1-hexene, styrene) in 1,2,2-trifluorotrichloroethane led to the selective formation of β-iodoalkyl trifluoroacetates or the ditrifluoroacetates of diols.In the reaction with 1-hexene a third direction is possible, i.e., the formation of the mixed acetic acid and trifluoroacetic diesters of 1,2-hexanediol.During the oxidation of styrene the formation of the geminal diester 1,1-ditrifluoroacetoxy-2-phenylethane is observed.The reaction takes place with the intermediate formation of compounds of monovalent iodine or a complex of polyvalent iodine, depending on the ratio of the reagents.

BROMO- AND IODOFUNCTIONALIZATION OF OLEFINS BY MEANS OF THE MERCURY(II) SALT-HALOGEN COMBINATION

Mercury(II) salts (fluoride, chloride, bromide, formate, acetate, trifluoroacetate, propionate, benzoate, nitrate, methanesulphonate, toluene-p-sulphonate, thiocyanate, and toluene-p-sulphinate) reacted with monoolefines and bromine or iodine to give 1,2-bifunctionalized products resulting from the addition of the halogen and the mercury(II) salt anion selectively.The addition was regiospecific for styrene and for 3,3-dimethylbut-1-ene affording Markownikoff type products, respectively.In the case of hex-1-ene both regioisomers were obtained.For cyclic alkenes trans-1,2-derivatives were stereoselectively obtained.Cycloocta-1,5-diene gave the monoaddition products.Buta-1,3-diene underwent mainly 1,2-addition and allylic derivatives gave the corresponding 1,2,3-trifunctionalized compounds.A possible ionic mechanism is proposed to explain the obtained addition products.