41109-94-8

Basic information

• Product Name: (2E,4E)-2-cyano-5-phenyl-2,4-pentadienoic acid methyl ester
• Synonyms: (2E,4E)-2-cyano-5-phenyl-2,4-pentadienoic acid methyl ester
• CAS NO: 41109-94-8
• Molecular Weight: 213.236
• Mol File: 41109-94-8.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (2E,4E)-2-cyano-5-phenyl-2,4-pentadienoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2E,4E)-2-cyano-5-phenyl-2,4-pentadienoic acid methyl ester(41109-94-8)
• EPA Substance Registry System: (2E,4E)-2-cyano-5-phenyl-2,4-pentadienoic acid methyl ester(41109-94-8)

Safety Data

• Hazardous Substances Data: 41109-94-8(Hazardous Substances Data)

Usage

General Description

"(2E,4E)-2-cyano-5-phenyl-2,4-pentadienoic acid methyl ester" is a chemical compound with a molecular formula of C12H9NO2. It is a methyl ester derivative of pentadienoic acid, specifically a cyanophenylpentadienoic acid. (2E,4E)-2-cyano-5-phenyl-2,4-pentadienoic acid methyl ester is commonly used in organic synthesis and as a starting material in various chemical reactions. It is known for its potential applications in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, it has been studied for its potential biological activities and pharmacological properties. However, caution should be taken when handling this compound, as it may pose health hazards if not handled properly. Overall, "(2E,4E)-2-cyano-5-phenyl-2,4-pentadienoic acid methyl ester" is a versatile chemical with diverse potential uses in the field of chemistry and pharmaceuticals.

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 105-34-0 methyl 2-cyanoacetate 
• 60-29-7 diethyl ether 
• 109-89-7 diethylamine 
• 41109-94-8 5t-phenyl-2-cyano-pentadien-(2ξ.4)-oic acid-(1)-methyl ester 
• 99686-39-2 (E)-2-bromo-3-phenylprop-2-enal 
• 4364-06-1 cinnamaldehyde dimethylacetal 
• 372-09-8 cyanoacetic acid 
• 4364-06-1 (E)-cinnamaldehyde dimethylacetal 
• 57194-69-1 cinnamaldehyde 

Downstream Products

• 41109-94-8 5c-phenyl-2-cyano-pentadien-(2ξ.4)-oic acid-(1)-methyl ester 

Relevant articles and documents

One-Pot Synthesis of γ-Azidobutyronitriles and Their Intramolecular Cycloadditions

Efficient gram-scale, one-pot approaches to azidocyanobutyrates and their amidated or decarboxylated derivatives have been developed, starting from commercially available aldehydes and cyanoacetates. These techniques combine (1) Knoevenagel condensation,

Synthesis of (E)-α,β-unsaturated carboxylic esters derivatives from cyanoacetic acid via promiscuous enzyme-promoted cascade esterification/Knoevenagel reaction

A new enzymatic protocol based on lipase-catalyzed cascade toward (E)-α,β-unsaturated carboxylic esters is presented. The proposed methodology consists of elementary organic processes starting from acetals and cyanoacetic acid leading to the formation of desired products in a cascade sequence. The combination of enzyme promiscuous abilities gives a new opportunity to synthesize complex molecules in the one-pot procedure. Results of studies on the influence of an enzyme type, solvent, and temperature on the cascade reaction course are reported. The presented methodology provides meaningful qualities such as significantly simplified process, excellent E-selectivity of obtained products and recycling of a biocatalyst.

Lewis Acid Triggered Vinylcyclopropane-Cyclopentene Rearrangement

We report a mild Lewis acid induced isomerization of donor-acceptor cyclopropanes, containing an alkenyl moiety and diverse electron-withdrawing group(s) at the adjacent positions, into substituted cyclopentenes. We have found that 1,1,2-trisubstituted cy