21143-57-7

Upstream product

• 21143-56-6 (2-Benzyl-4-chloro-phenyl)-acetonitrile 
• 41148-47-4 4-chloro-2-benzoylphenylacetic acid 
• 59749-79-0 5-chloro-3-phenyl-1H-indene 
• 21143-54-4 2-Benzyl-4-chlorobenzyl alcohol 
• 21143-55-5 2-Benzyl-1-bromomethyl-4-chloro-benzene 
• 21143-53-3 methyl 2-benzyl-4-chlorobenzoate 
• 33184-56-4 2-benzoyl-4-chlorobenzoic acid 
• 81992-90-7 2-benzyl-4-chloro-benzoic acid 

Relevant academic research and scientific papers

Design, synthesis and SAR of phenylamino-substituted 5,11-dihydro-dibenzo[a,d]cyclohepten-10-ones and 11H-dibenzo[b,f]oxepin-10-ones as p38 MAP kinase inhibitors

The p38 MAP kinase is a key enzyme in inflammatory diseases as it is involved in the biosynthesis of proinflammatory cytokines such as TNF-α and IL-1β. Small molecule p38 inhibitors suppress the production of these cytokines and therefore p38 is a promisi

2-(Arylmethyl)arylacetic Acids as Potential Antiinflammatory Agents

The title compounds 2 have been synthesized and tested for antiinflammatory activity.The synthetic method, consisting of the chemical sequence 3-aryl-1H-indenes (4) 2-(aroyl)arylacetic acids (5) 2, appears to be of value because of its simplicity