41164-59-4

Usage

Uses

Used in Pharmaceutical Applications:
LL P880 beta is used as an active pharmaceutical ingredient for its potential therapeutic effects. It is presumed to share a common activity profile with pestalotin, which has been studied for its various medicinal properties.
Used in Drug Delivery Systems:
In the field of drug delivery, LL P880 beta is used as a carrier for enhancing the delivery, bioavailability, and therapeutic outcomes of various drugs. Its unique properties make it a promising candidate for improving the efficacy of pharmaceuticals and reducing their side effects.

InChI:InChI=1/C11H18O5/c1-3-4-8(12)11(14)9-5-7(15-2)6-10(13)16-9/h6,8-9,11-12,14H,3-5H2,1-2H3

Upstream product

• 67-56-1 methanol 
• 157189-70-3 Acetic acid (1S,2R)-2-acetoxy-1-[(S)-6-oxo-4-(toluene-4-sulfonyl)-3,6-dihydro-2H-pyran-2-yl]-pentyl ester 
• 131087-30-4 6-((1S,2R)-1,2-Bis-benzyloxy-pentyl)-4-hydroxy-5,6-dihydro-pyran-2-one 
• 131087-27-9 (2S,3S,4R)-1,2-Cyclopentylidenedioxy-3,4-dibenzyloxyheptane 
• 131087-28-0 (2S,3S,4R)-3,4-Dibenzyloxy-1,2-dihydroxyheptane 
• 131087-26-8 (2S,3S,4R)-3-Benzyloxy-1,2-cyclopentylidenedioxy-4-hydroxyheptane 
• 131087-29-1 (2S,3R)-2,3-Dibenzyloxyhexanal 
• 23786-93-8 1,1-diethoxy-cyclopentane 
• 157189-67-8 1-[(1S,3R,5S,7R)-3-(Toluene-4-sulfonyl)-6,8-dioxa-bicyclo[3.2.1]oct-7-yl]-butan-1-one 
• 157189-66-7 (1S,3R,5S,7R)-3-(Toluene-4-sulfonyl)-6,8-dioxa-bicyclo[3.2.1]octane-7-carbaldehyde 
• 89927-11-7 7-mesyloxymethyl-3-tosyl-6,8-dioxabicyclo<3.2.1>octane 
• 131087-31-5 (6RS,1'S,2'R)-6-(1',2'-Dibenzyloxypentyl)-5,6-dihydro-4-methoxypyrane-2-one 
• 157189-63-4 (R)-1-[(1S,3R,5S,7S)-3-(Toluene-4-sulfonyl)-6,8-dioxa-bicyclo[3.2.1]oct-7-yl]-butan-1-ol 
• 157189-68-9 Acetic acid (1R,2R)-2-acetoxy-1-[(2S,4R)-4-(toluene-4-sulfonyl)-3,4-dihydro-2H-pyran-2-yl]-pentyl ester 

Relevant academic research and scientific papers

Divergent synthesis of (6S,1′S,2′R)-hydroxypestalotin via tandem conjugate addition-lactonization sequence

The stereoselective synthesis of (6S,1′S,2′R)-hydroxypestalotin from trans-hex-2-en-1-ol utilizing asymmetric dihydroxylation and Luche's reduction and tandem conjugative addition-lactonization as the key steps is reported.

Highly stereoselective synthesis and structural confirmation of a fungal metabolite, LL-P880β

A fungal metabolite, LL-P880β [6S-(1'S,2'R-dihydroxypentyl)-4-methoxy- 5,6-dihydropyran-2-one] (1), was synthesized unambiguously from diethyl (R,R)-tartrate (3) as a chiral pool via highly stereoselective construction of the C7'-asymmetric carbon of the

Total Synthesis of (6S,1'S,2'R)-6-(1',2'-Dihydroxypentyl)-4-methoxy-5,6-dihydropyrane-2-one (LL-P880β) and Its C6-Epimer, a Fungal Metabolite from Penicillium sp.

A fungal metabolite, (6S,1'S,2'R)-6-(1',2'-dihydroxypentyl)-4-methoxy-5,6-dihydropyrane-2-one (LL-P880β, I), and its C6-epimer (II) were synthesized by the chiron approach.The key intermediate, (2S,3R)-2,3-dihydroxyhexanal derivative (3), was p