41175-40-0

Basic information

• Product Name: 4-AMINO-3-PHENYL-1-BUTANOL
• Synonyms: 4-AMINO-3-PHENYL-1-BUTANOL;4-AMINO-3-PHENYLBUTAN-1-OL
• CAS NO: 41175-40-0
• Molecular Formula: C₁₀H₁₅NO
• Molecular Weight: 165.23
• Mol File: 41175-40-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 295.9°C at 760 mmHg
• Flash Point: 132.7°C
• Appearance: /
• Density: 1.051g/cm³
• Vapor Pressure: 0.000671mmHg at 25°C
• Refractive Index: 1.55
• CAS DataBase Reference: 4-AMINO-3-PHENYL-1-BUTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-3-PHENYL-1-BUTANOL(41175-40-0)
• EPA Substance Registry System: 4-AMINO-3-PHENYL-1-BUTANOL(41175-40-0)

Safety Data

• Hazardous Substances Data: 41175-40-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H15NO/c11-8-10(6-7-12)9-4-2-1-3-5-9/h1-5,10,12H,6-8,11H2

Upstream product

• 140-29-4 phenylacetonitrile 
• 22485-02-5 tert-butyl 3-cyano-3-phenylpropanoate 
• 41441-40-1 ethyl 3-phenyl-4-nitrobutanoate 
• 14025-83-3 3-cyano-3-phenylpropanoic acid ethyl ester 

Downstream Products

• 1171518-22-1 benzyl 3-phenylpyrrolidine-1-carboxylate 
• 147410-43-3 tert-butyl 3-phenylpyrrolidine-1-carboxylate 

Relevant articles and documents

FUSED [1,2,4]THIADIAZINE DERIVATIVES WHICH ACT AS KAT INHIBITORS OF THE MYST FAMILY

A compound of formula (I): which inhibits the activity of one or more KATs of the MYST family, i.e., TIP60, KAT6B, MOZ, HBO1 and MOF.

Orthoester in Cyclodehydration of Carbamate-Protected Amino Alcohols under Acidic Conditions

The first acid-promoted reaction system to form azaheterocycles from N -carbamate-protected amino alcohols is described. The reaction involves the activation of the hydroxyl group via the use of orthoesters. Despite the reduced nucleophilicity of carbamate nitrogen, this reaction system provides several types of pyrrolidines and piperidines in good to high yields. Using this protocol, prolinol derivatives can also be synthesized from carbamate-protected amino diols with regio- and stereoselectivity.