41208-22-4Relevant articles and documents
Dehydrogenation of cyclic tertiary amines with neighbouring of enantiomeric nucleophiles
M?hrle, Hans,Berkenkemper, Thomas
, p. 435 - 443 (2007/10/03)
For stereochemical investigation of their dehydrogenation, the enantiomers of the aminoalcohols 1, 2, and 3 were prepared from optically active sources, while the enantiomers of the diamines 8 and 9 were available by resolution of the racemates. The pure antipodes of 1, 2, and 3 reacted with mercury(II)-EDTA by a twofold dehydrogenation via intermediate participation of the neighbouring alcoholic group to the optically active lactams 5, 6, and 7 under complete retention of configuration. In the same manner the diamines 8 and 9 generated by four electron withdrawal the cycloamidines 10 and 11.