412271-30-8

Upstream product

• 75-30-9 2-iodo-propane 
• 100-52-7 benzaldehyde 
• 104-94-9 4-methoxy-aniline 
• 1613-90-7 4-methoxy-N-[(E)-phenylmethylidene]aniline 
• 1068-55-9 isopropylmagnesium chloride 
• 783-08-4 [4-(benzylideneamino)phenyl]methanol 
• 1539-32-8 4-isopropyl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester 
• 57181-82-5 4-bromo-isobutylbenzene 
• 5720-07-0 4-methoxyphenylboronic acid 

Downstream Products

• 1562-94-3 4,4'-azoxy anisole 
• 611-70-1 phenyl isopropyl ketone 

Relevant academic research and scientific papers

Radical alkylation of imines with 4-alkyl-1,4-dihydropyridines enabled by photoredox/br?nsted acid cocatalysis

Radical alkylation of imines with 4-alkyl-1,4-dihydropyridines cocatalyzed by iridium/ruthenium complex and Br?nsted acid under visible light irradiation has been achieved. Both aldimines and ketimines can undergo this transformation. Common functional groups, such as hydroxyl groups, ester, amide, ether, cyanide, and heterocycles, can be tolerated in this reaction. A variety of structurally diverse amines (57 examples) have been produced with up to 98% isolated yields using this method.

Synthesis of Hindered Anilines: Three-Component Coupling of Arylboronic Acids, tert-Butyl Nitrite, and Alkyl Bromides

The synthesis of sterically hindered amines has been a significant challenge in organic chemistry. Herein, we report a modular, three-component coupling that constructs two carbon-nitrogen bonds including a sterically hindered Csp3-N bond using commercially available materials. This process uses an earth-abundant copper catalyst and mild reaction conditions, allowing access to a variety of complex aromatic amines.

Synthesis, oxidation and photophysical properties of novel derivatives of acyclic aromatic amines

Conjugated acyclic arylamine derivatives, N-(4-methylphenyl)-N-(2-methyl-1- phenylpropyl)amine and N-(4-methoxyphenyl)-N-(2-methyl-1-phenylpropyl)amine, have been synthesized and characterized. Their photophysical properties have been investigated in polar methanol and non-polar cyclohexane solutions, and in PS and PMMA polymer matrices. The influence of the environment polarity as well as of the substituent in para-position of the aryl on the absorption, emission spectra and the fluorescence quantum yield has been studied. In the absorption and emission spectra, the observed absorption and emission band maxima were red shifted and the observed quantum yield was higher in the polar solution in comparison with the non-polar solution or polymer matrices. The distance of short- and long-wavelength absorption maxima in the methoxy derivative was larger and the emission band was red shifted in comparison with the methyl derivative. Chemical and photochemical oxidation of the prepared amines gives unstable nitroxides. High intramolecular quenching was observed in polymer matrix after photochemical oxidation of the amines.

Solutions of anhydrous lanthanide salts and its preparation

The present invention relates to anhydrous solutions of MX 3 €￠z LiA in a solvent, wherein M is a lanthanide including lanthanum, or yttrium or indium; z > 0; and X and A are independently or both monovalent anions, preferably Cl, Br or I. The solution is readily prepared by dissolving or suspending MX 3 or its hydrate and z equiv LiA in water or hydrophilic solvents, or mixtures thereof, removing the solvent under vacuum and dissolving the resulting powder in another solvent. The solution of MX 3 €￠z LiA can advantageously be used e.g. in addition reactions of Grignard reagents to ketones and imines. Even the catalytic use of MX 3 €￠z LiA is possible. Also claimed are a method for preparing the anhydrous solutions, the use of such solution in a chemical reaction and chemical compositions MX 3 €￠z LiA, with M, z, X and A as indicated above.

Soluble lanthanide salts (LnCl3,·2 LiCl) for the improved addition of organomagnesium reagents to carbonyl compounds

(Chemical Equation Presented) Easy-to-prepare solutions of LnCl 3·2 LiCl (Ln = La, Ce, Nd) (0.3-0.5 M in THF) are a unique source of soluble lanthanide salts with versatile applications in organic synthesis. These salts can serve as promoters or catalysts for the addition of organometallic compounds to sterically hindered, enolizable or α,β-unsaturated ketones or imines.

Br?nsted acid catalysis: Organocatalytic hydrogenation of imines

A new Br?nsted acid catalysed hydrogenation of imines with Hantzsch dihydropyridine as the hydrogen source has been developed. Diphenyl phosphate (DPP) and various other acids catalyse this first metal-free hydrogen transfer to give various amines under m

One-pot four-component reaction: Aqueous TiCl3/PhN 2+-mediated alkyl radical addition to imines generated in situ

(Chemical Equation Presented) Ti(III)-induced free-radical decomposition of a phenyldiazonium salt, followed by phenyl radical iodine-atom abstraction from alkyl iodides, leads to a one-pot selective alkyl radical addition to the C-atom of imines generated in situ under aqueous acidic conditions.

Nucleophilic addition of organomagnesiums to aldimines: Scandium triflate (Sc(OTf)3) as an effective catalyst

The 1,2-addition of organomagnesium reagents to p-methoxyphenyl (PMP)amine-derived aldimines proceeded effectively in the presence of catalytic amounts of Sc(OTf)3.