41270-62-6

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-6-phenylpyrazine serves as a crucial building block in the synthesis of pharmaceuticals, acting as an intermediate for the development of potential drug candidates. Its unique structure allows for the creation of new compounds with therapeutic properties, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Chloro-6-phenylpyrazine is utilized in the synthesis of various organic compounds, playing a significant role in the development of new agrochemical products. Its versatility in chemical reactions makes it a valuable component in the formulation of effective and targeted agrochemicals.
Used in Flavor and Fragrance Industry:
2-Chloro-6-phenylpyrazine also finds application in the food industry as a flavor and fragrance ingredient. Its distinct chemical properties contribute to the creation of unique and appealing taste and scent profiles, enhancing the sensory experience of food products.
Despite being a relatively rare compound, 2-Chloro-6-phenylpyrazine's potential applications in various fields are significant due to its distinctive chemical structure and properties. Its versatility and adaptability in different chemical reactions make it a valuable asset in the development of innovative products across multiple industries.

Upstream product

• 58861-89-5 2-phenylpyrazine N⁽¹⁾-oxide 
• 1074-12-0 phenylglyoxal hydrate 
• 4774-14-5 2,6-dichloropyrazine 
• 98-80-6 phenylboronic acid 
• 58861-94-2 2-phenylpyrazine 4-oxide 
• 2882-18-0 2-hydroxy-3-phenylpyrazine 
• 58861-87-3 2-chloro-3-phenyl-pyrazine 4-oxide 
• 29460-97-7 2-phenylpyrazine 
• 160315-09-3 2-acetoxy-3-phenylpyrazine 
• 160315-17-3 2-acetoxy-6-phenylpyrazine 
• 41270-65-9 2-chloro-3-phenylpyrazine 
• 66769-60-6 3-chloro-5-phenylpyrazine 1-oxide 
• 41270-59-1 6-phenyl-1H-pyrazin-2-one 

Downstream Products

• 1172621-06-5 tert-butyl 5-methyl-3-(6-phenylpyrazin-2-ylamino)-1H-pyrazole-1-carboxylate 

Relevant academic research and scientific papers

Synthesis of Chiral Piperazines via Hydrogenation of Pyrazines Activated by Alkyl Halides

A facile method has been developed for the synthesis of chiral piperazines through Ir-catalyzed hydrogenation of pyrazines activated by alkyl halides, giving a wide range of chiral piperazines including 3-substituted as well as 2,3- and 3,5-disubstituted

CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS

The present invention provides a compound of Formula (I): and pharmaceutically acceptable salts thereof, as further described herein. Also provided are formulations comprising compounds of formula I, and a method to use such compounds for treating a disease or condition mediated by Provirus Integration of Maloney Maloney Kinase (PIM Kinase), GSK3, PKC, KDR, PDGFRa, FGFR3, FLT3, or cABL.

TETRASUBSTITUTED CYCLOHEXYL COMPOUNDS AS KINASE INHIBITORS

The present invention provides a compound of formula (I): as further described herein, and pharmaceutically acceptable salts, enantiomers, rotamers, tautomers, or racemates thereof. Also provided are methods of treating a disease or condition mediated by PIM kinase using the compounds of Formula I, and pharmaceutical compositions comprising such compounds.

PYRAZOLE PYRAZINE AMINE COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS THEREOF AND METHODS OF TREATMENT THEREWITH

Provided herein are Pyrazole Pyrazine Amine Compounds having the following structure:Formula (I). Wherein Q and R1-R3 are as defined herein, compositions comprising an effective amount of a Pyrazole Pyrazine Amine Compound and methods for treating or preventing inflammatory conditions, immunological conditions, cancer, neurodegenerative diseases, age-related diseases, cardiovascular diseases and metabolic conditions, or conditions treatable or preventable by inhibition of an IKK, or an IKK pathway, comprising administering an effective amount of a Pyrazole Pyrazine Amine Compound to a patient in need thereof.

AZAADAMANTANE DERIVATIVES AND METHODS OF USE

The invention relates to compounds that are azaadamantane derivatives, particularly ether- or amine-substituted azaadamantane derivatives and salts and prodrugs thereof, compositions comprising such compounds, methods of using such compounds and compositi

Some Reactions of Mono Substituted Pyrazine Monoxides

The reactions of the monoxides of propylpyrazine and phenylpyrazine with phosphoryl chloride or acetic anhydride were investigated.Except in the case of the reaction of 2-propylpyrazine 1-oxide with acetic anhydride, chlorination or acetoxylation occurred