160315-17-3

Basic information

• Product Name: 2-acetoxy-6-phenylpyrazine
• CAS NO: 160315-17-3
• Molecular Weight: 214.224
• Mol File: 160315-17-3.mol

Chemical Properties

• CAS DataBase Reference: 2-acetoxy-6-phenylpyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-acetoxy-6-phenylpyrazine(160315-17-3)
• EPA Substance Registry System: 2-acetoxy-6-phenylpyrazine(160315-17-3)

Safety Data

• Hazardous Substances Data: 160315-17-3(Hazardous Substances Data)

Upstream product

• 58861-94-2 2-phenylpyrazine 4-oxide 
• 2882-18-0 2-hydroxy-3-phenylpyrazine 
• 58861-87-3 2-chloro-3-phenyl-pyrazine 4-oxide 
• 29460-97-7 2-phenylpyrazine 
• 160315-09-3 2-acetoxy-3-phenylpyrazine 
• 1074-12-0 phenylglyoxal hydrate 
• 41270-65-9 2-chloro-3-phenylpyrazine 
• 108-24-7 acetic anhydride 
• 58861-89-5 2-phenylpyrazine N⁽¹⁾-oxide 

Downstream Products

• 32493-80-4 2,3-dichloro-5-phenylpyrazine 
• 64163-09-3 2,5-dichloro-6-phenylpyrazine 
• 76809-46-6 2-hydroxy-6-phenylpyrazine 4-oxide 
• 41270-62-6 2-chloro-6-phenylpyrazine 
• 66769-60-6 3-chloro-5-phenylpyrazine 1-oxide 
• 41270-59-1 6-phenyl-1H-pyrazin-2-one 

Relevant articles and documents

Studies on Pyrazines. Part 28. Deoxydative Acetoxylation of Pyrazine N-Oxides

Deoxydative acetoxylation of 3-methoxy-, 3-phenyl-, 3-methyl-, 3-chloro-, and 3-methoxycarbonylpyrazine 1-oxides furnished predominantly 2-acetoxy-6-substituted pyrazines, some of which were more selectively prepared by addition of zinc bromide and triethylamine to the reaction.Regioselectivity of the acetoxylation is discussed based upon heat of formation by AM1 and AM1-COSMO for all possible isomers of each set.

Some Reactions of Mono Substituted Pyrazine Monoxides

The reactions of the monoxides of propylpyrazine and phenylpyrazine with phosphoryl chloride or acetic anhydride were investigated.Except in the case of the reaction of 2-propylpyrazine 1-oxide with acetic anhydride, chlorination or acetoxylation occurred