4128-00-1

Usage

Uses

Used in Organic Synthesis:
(S)-3-Amino-2-pyrrolidinone is used as a chiral building block in the synthesis of more complex molecules. Its enantiomerically pure nature makes it a valuable component in the creation of various organic compounds, contributing to the development of new pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
(S)-3-Amino-2-pyrrolidinone is used as a key intermediate in the synthesis of pharmaceutical compounds. Its unique structure and reactivity allow for the creation of new drug candidates with potential therapeutic applications, making it an essential tool in the field of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, (S)-3-Amino-2-pyrrolidinone is used as a precursor in the development of new agrochemical products. Its role in the synthesis of complex molecules enables the creation of innovative pesticides, herbicides, and other crop protection agents, enhancing agricultural productivity and sustainability.
Used in Specialty Chemicals:
(S)-3-Amino-2-pyrrolidinone is employed as a building block in the synthesis of specialty chemicals, such as fragrances, dyes, and other fine chemicals. Its versatility in organic synthesis allows for the development of novel compounds with unique properties and applications, contributing to the advancement of various industries.

Upstream product

• 141-52-6 sodium ethanolate 
• 103668-08-2 ethyl (S)-2,4-diaminobutanoate dihydrochloride 
• 1482-98-0 L-2,4-diaminobutyric acid monohydrochloride 
• 1758-80-1 L-2,4-diaminobutyrate 
• 1482-98-0 (S)-2,4-diaminobutyric acid dihydrochloride 

Downstream Products

• 146679-04-1 (S)-3-(formylamino)-2-pyrrolidinone 
• 114200-45-2 3(S)-amino>-2-oxopyrrolidine 
• 188174-94-9 (S)-3-[4-(3-fluorobenzyloxy)-benzylamino]-pyrrolidin-2-one 
• 1421583-02-9 4-(5-{(1R)-1-[4-(cyclopropylcarbonyl)phenoxy]propyl}-1,2,4-oxadiazol-3-yl)-2-fluoro-N-[(3S)-2-oxopyrrolidin-3-yl]benzamide 
• 1421583-05-2 4-(5-{(1R)-1-[4-(cyclopropylcarbonyl)phenoxy]ethyl}-1,2,4-oxadiazol-3-yl)-2-fluoro-N-[(3S)-2-oxopyrrolidin-3-yl]benzamide 

Relevant academic research and scientific papers

ACC INHIBITORS AND USES THEREOF

The present invention provides compounds I and II useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.

COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS

A compound is represented by Structural Formula (I), or a pharmaceutically acceptable salt thereof, wherein the variables of Structural Formula (I) are as described in the specification and the claims. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier of excipient. A method of treating a HCV infection in a subject comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of inhibiting or reducing the activity of HCV polymerase in a subject or in a biological in vitro sample comprises administering to the subject or to the sample a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof.

Kinase inhibitor compounds

The invention relates to compounds, compositions comprising the compounds, and methods of using the compounds and compound compositions. The compounds, compositions, and methods described herein can be used for the therapeutic modulation of kinase-mediated processes, and treatment of disease and disease symptoms, particularly those mediated by certain kinase enzymes.

KINASE INHIBITOR COMPOUNDS

The invention relates to compounds, compositions comprising the compounds, and methods of using the compounds and compound compositions. The compounds, compositions, and methods described herein can be used for the therapeutic modulation of kinase-mediated processes, and treatment of disease and disease symptoms, particularly those mediated by certain kinase enzymes.

P38 INHIBITORS AND METHODS OF USE THEREOF

Compounds of formula (I): in which A, B, X, Ar1, R8 and R4 have any of the meanings given in the specification, are inhibitors of p38 useful in the treatment and prevention of various disorders mediated by p38.

3-aminopyrrolidone derivatives

This invention is related to compounds and use of 3-aminopyrrolidone derivatives and analogues of the following general formula (I)???whereinmis an integer from 1 to 3Xis methylene, oxygen, sulphur or a NR6 group;R1is a straight or branched C1-C8 alkyl or C3-C8 alkenylene or C3-C8 alkynylene chain, optionally substituted with CF3, phenyl, phenoxy or naphthyl, the aromatic rings optionally substituted by one or more C1-C4 alkyl, halogens, trifluoromethyl, hydroxy or C1-C4 alkoxy groups;R2, R3are independently hydrogen, a C1-C3 alkyl chain, halogen, trifluoromethyl, hydroxy or C1-C4 alkoxy groups;R4, R5, R6are independently hydrogen or C1-C6 alkyl;???and the pharmaceutically acceptable salts thereof that are active as sodium and/or calcium channel modulators and therefore useful in preventing, alleviating and curing a wide range of pathologies, including, but not limited to, neurological, psychiatric, cardiovascular, inflammatory, ophthalmic, urologic, metabolic and gastrointestinal diseases, where the above mechanisms have been described as playing a pathological role.

Absolute configuration of α-phthalimido carboxylic acid derivatives from circular dichroism spectra

It is demonstrated that the Cotton effects due to the 220 nm phthalimide π-π* transition observed for a series of derivatives of α- phthalimidocarboxylic acids unequivocally reflect the amino acid absolute configuration. This method is based on the exciton coupling of the allowed transitions of the phthalimide and the carboxylic acid derivative chromophores. (C) 1999 Elsevier Science Ltd.

The synthesis of unusual tetrahydropyrimidine amino acids

The synthesis of derivatives of 2-(1-an-aminoalkyl)-4-carboxy-3,4,5,6-tetrahydropyrimidines, unusual amino acids isolated from bacterial siderophores, is described, from condensation of N-protected amino acids imidates or thiomidates with 2,4-diaminobutyrylglycine methyl ester.