4141-12-2 Usage
Uses
Used in Pharmaceutical Industry:
Benzoic acid, 2-[[(methylamino)carbonyl]amino]-, is used as an intermediate in the synthesis of various pharmaceuticals due to its versatile chemical structure and potential therapeutic effects. Its anti-inflammatory and anti-microbial properties make it a valuable component in the development of new drugs for treating a range of diseases.
Used in Agrochemical Industry:
In the agrochemical sector, Benzoic acid, 2-[[(methylamino)carbonyl]amino]-, serves as an intermediate in the production of various agrochemicals. Its ability to combat microbial growth and inflammation can be harnessed to develop effective agents for crop protection and enhancement of agricultural yields.
Used in Food Industry:
Benzoic acid, 2-[[(methylamino)carbonyl]amino]-, is used as a food preservative to extend the shelf life of various food products. Its properties help prevent spoilage and growth of harmful microorganisms, ensuring the safety and quality of the food items.
Used in Cancer Research and Drug Development:
Benzoic acid, 2-[[(methylamino)carbonyl]amino]is being explored for its potential role in the development of new drugs for the treatment of cancer. Its anti-inflammatory and anti-microbial properties, along with its chemical structure, make it a promising candidate for further research and development in oncology.
Used in Treatment of Various Diseases:
Benzoic acid, 2-[[(methylamino)carbonyl]amino]-, is also being studied for its potential use in the treatment of various diseases beyond cancer, including inflammatory and microbial infections, due to its inherent therapeutic properties.
Check Digit Verification of cas no
The CAS Registry Mumber 4141-12-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,4 and 1 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4141-12:
(6*4)+(5*1)+(4*4)+(3*1)+(2*1)+(1*2)=52
52 % 10 = 2
So 4141-12-2 is a valid CAS Registry Number.
4141-12-2Relevant academic research and scientific papers
Synthesis and evaluation of highly selective quinazoline-2,4-dione ligands for sphingosine-1-phosphate receptor 2
Gropler, Robert J.,Klein, Robyn S.,Liu, Hui,Luo, Zonghua,Tu, Zhude,Yu, Yanbo
supporting information, p. 202 - 207 (2022/03/30)
A series of twenty-nine new quinazoline-2,4-dione compounds were synthesized and their IC50 values for binding toward sphingosine-1-phosphate receptor 2 (S1PR2) were determined using a [32P]S1P binding assay. Seven compounds 2a, 2g, 2h, 2i, 2j, 2k, and 5h exhibit high S1PR2 binding potencies (IC50 values 98%), and high molar activity (153-222 GBq μmol-1, at the end of bombardment). [11C]2a and [11C]2i were further evaluated by the ex vivo biodistribution study. The results showed that both tracers have low brain uptake, preventing their potential for neuroimaging application. Further explorations of this class of S1PR2 PET tracers in peripheral tissue diseases are underway. This journal is
INTRAMOLECULAR NUCLEOPHILIC ATTACK ON CARBOXYLATE BY UREIDE ANION. GENERAL ACID-BASE CATALYSIS OF THE ALKALINE CYCLISATION OF 2,2,3,5-TETRAMETHYLHYDANTOIC ACID
Blagoeva, Iva B.,Pojarlieff, Ivan G.
, p. 745 - 752 (2007/10/02)
The cyclisation of the title compound to the corresponding hydantoin is a model for the carboxylation of biotin by hydrogen carbonate.The reaction is rapid over the whole pH range, and is catalysed by both general acids and general bases.Above ph 9.2 the reaction is first order in hydroxide, which is shown to act as a general base.The prefered mechanism is specific base-general acid catalysis, involving nucleophilic attack by the ureide anion on the ionised carboxy group, assisted by proton transfer from the general acid.This defines also the mechanism of the reverse reaction, and clarifies for the first time the role of the second hydroxide ion in the ->2 term for the hydrolysis of amides with good leaving groups.
