41433-81-2Relevant articles and documents
Synthesis, characterization and blood compatibilities of novel segmented polyurethanes containing poly (butadiene) soft segments and phosphatidylcholine analogues in the main chains and long-chain alkyl groups in the side chains
Korematsu, Arata,Li, Yu-Jun,Murakami, Takayuki,Sakurai, Ikuko,Kodama, Makoto,Nakaya, Tadao
, p. 647 - 653 (1999)
New segmented polyurethanes (SPUs) containing poly(butadiene) (PBD) soft segments and phospholipid moieties in the main chains and long-chain alkyl groups in the side chains were synthesized. The phospholipid moieties include bis [2-(2-hydroxyethyldimethylammonio)ethyl] 2-octylpropane- 1,3-diyl bis(phosphate) (OcPDP), bis [2-(2-hydroxyethyldimethylammonio)ethyl]2- oleylpropane-1,3-diyl bis (phosphate) (O1PDP) and bis[2-(2- hydroxyethyldimethylammonio)ethyl] 2-cetylpropane-1,3-diyl bis(phosphate) (CPDP). The bulk characterization of synthesized SPUs was investigated by infrared (IR) spectroscopy and gel-permeation chromatography (GPC). The mechanical properties were evaluated by dynamic viscoelasticity and tensile measurements. The existence of phospholipid analogous groups on the surface of these SPUs was revealed by attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectroscopy (XPS) and contact angle measurements. The blood compatibilities of the new polymers were evaluated by platelet rich plasma (PRP) contact studies and viewed by scanning electron microscopy (SEM) using medical grade BioSpan and non- phospholipid polyurethane as references. These new materials have good surfaces in terms of platelet adhesion, and the morphology of adhered platelets undergoes a relatively low degree of variation.
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Skinner,Stuart
, p. 2993 (1941)
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Synthesis of new lipophilic Ortho-dicarboranes
Garrigues, Emmanuelle,Souchard, Jean-Pierre,Nepveu, Francoise
, p. 4489 - 4492 (1998)
The synthesis of several new lipoidal dicarborane compounds prepared by reaction of decaborane with several fatty mona- and bis-alkyl-1,3-diols is described.
4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO
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Page/Page column 323, (2021/07/10)
Disclosed are halogen containing nucleotide and nucleoside therapeutic compositions and uses related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of viral infections. Such viral infections can include tongaviridae, bunyaviridae, arenaviridae, coronaviridae, flaviviridae, picornaviridae, Eastern, Western, and Venezuelan Equine Encephalitis (EEE, WEE and VEE, respectively), Chikungunya fever (CHIK), Ebola, Influenza, RSV, and Zika virus infections.
NOVEL XYLENE-BASED AMPHIPHILIC COMPOUND AND USE THEREOF
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Paragraph 0178; 0179; 0216; 0231; 0256, (2018/10/19)
The present invention relates to a xylene-based amphiphilic compound, a method for preparing the same, and a method for extracting, solubilizing, stabilizing or crystallizing a membrane protein using the same. By using the xylene-based compound according to the present invention, a membrane protein may be stably stored in an aqueous solution for a long time, and may be applied in functional and structural analyses. The structural and functional analysis of the membrane protein is one of the fields of highest interest in biology and chemistry, and the xylene-based compound according to the present invention can be applied in research on protein structure that is closely related to development of a new drug.