41440-05-5

Usage

Uses

Used in Pharmaceutical Industry:
5,7,8-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one is used as a pharmaceutical compound for its potential therapeutic effects. 5,7,8-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one's unique structure allows it to interact with various biological targets, making it a promising candidate for the development of new drugs.
Used in Antioxidant Applications:
In the field of nutrition and health, 5,7,8-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one is used as an antioxidant. Its ability to scavenge free radicals and protect cells from oxidative damage makes it a valuable ingredient in the development of health supplements and functional foods.
Used in Cosmetic Industry:
5,7,8-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one is used as an active ingredient in the cosmetic industry for its potential skin protective and anti-aging properties. Its antioxidant and anti-inflammatory activities contribute to its potential use in skincare products, promoting skin health and reducing the signs of aging.
Used in Agricultural Industry:
In agriculture, 5,7,8-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one can be used as a natural pesticide or fungicide due to its antimicrobial properties. Its ability to inhibit the growth of harmful microorganisms can help protect crops and improve their overall health and yield.
Used in Research and Development:
5,7,8-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one is also used as a research compound in various scientific studies. Its unique chemical structure and potential biological activities make it an interesting subject for further investigation, with the aim of discovering new applications and understanding its mechanisms of action.

InChI:InChI=1/C15H10O6/c16-8-3-1-7(2-4-8)12-6-10(18)13-9(17)5-11(19)14(20)15(13)21-12/h1-6,16-17,19-20H

Upstream product

• 97828-25-6 5,7-bis(benzyloxy)-2-(4-(benzyloxy)phenyl)-8-iodo-4H-chromen-4-one 
• 96333-59-4 5,7-bis(benzyloxy)-2-(4-(benzyloxy)phenyl)-4H-chromen-4-one 
• 88607-79-8 (E)-1-(2,4-bis(benzyloxy)-6-hydroxyphenyl)-3-(4-(benzyloxy)phenyl)prop-2-en-1-one 
• 4397-53-9 p-benzyloxybenzaldehyde 
• 18065-05-9 1-[2,4-bis(benzyloxy)-6-hydroxyphenyl]ethanone 
• 859076-89-4 1-(4-methoxy-phenyl)-3-(2,3,4,6-tetramethoxy-phenyl)-propane-1,3-dione 
• 10034-85-2 hydrogen iodide 
• 6601-66-7 6-demethoxytangeretin 

Downstream Products

• 529-53-3 scutellarein 
• 137231-94-8 Scutellaprostin C pentaacetate 
• 137231-93-7 Scutellaprostin B tetraacetate 
• 57096-02-3 5,7,4'-trihydroxy-8-methoxyflavone 
• 51876-19-8 5,7,8-trihydroxy-4'-methoxyflavone 
• 54917-70-3 5,7,8-triacetoxy-2-(4-acetoxy-phenyl)-chromen-4-one 
• 137231-84-6 Scutellaprostin B 

Relevant academic research and scientific papers

Preparation method and intermediates of flavonoids

The invention discloses a preparation method and intermediates of flavonoids. The preparation method comprises the following steps: in a solvent, in the presence of an acid, performing a ring-opening reaction and an elimination reaction on a compound 8 to obtain a compound 9. Raw materials used in the method are easy to acquire, and the method has high yields and simple post processes, and does not need column chromatography.

Preparation method of flavonoids

The invention discloses a preparation method of flavonoids. The method comprises the following step: in a solvent, in the presence of iodine and a silver salt or in the presence of iodine and a copper salt, performing an iodination reaction on a compound 1 to obtain a compound 2. Raw materials used in the method are easy to acquire, and the method has high yields and simple post processes, and does not need column chromatography.

Facile synthesis of norwogonin, isoscutellarein, and herbacetin

An expeditious synthesis of norwogonin, isoscutellarein, and herbacetin, has been accomplished by a strategy featuring a borylation of sterically hindered aryl iodide and a one-pot oxidation to generate the C-3 and C-8 OH groups. The total synthesis gives excellent yields and conventional flash column chromatography is not needed for purification.

Synthetic Studies of the Flavone Derivatives. VIII. Synthesis of Kanzakiflavones and Their Isomers

Kanzakiflavone-1 and -2, isolates from Iris Unguicularis, and their position isomers were synthesized to confirm the structures of the isolates.The differences among these flavones are discussed on the basis of spectral data.Keywords: kanzakiflavone-1; kanzakiflavone-2; 4',5-dihydroxy-7,8-methylenedioxyflavone; 6,7-methylenedioxy-4',5,8-trimethoxyflavone; 7,8-methylenedioxy-4',5,6-trimethoxyflavone; 3'-acetyl-4',5-dihydroxy-6,7-methylenedioxyflavone

Studies of the Selective O-Alkylation and Dealkylation of Flavonoids. VI. Demethylation of 8-Hydroxy-5,7-dimethoxyflavones with Anhydrous Aluminum Chloride or Bromide in Acetonitrile

The demethylation of seven 8-hydroxy-5,7-dimethoxyflavones with anhydrous aluminum chloride or bromide in acetonitrile was studied and the following results were obtained. (1) Anhydrous aluminum chloride in acetonitrile selectively split the 5-methoxyl group without cleavage of the 7-methoxyl group, and seven 5,8-dihydroxy-7-methoxy-flavones were quantitatively synthesized by the demethylation. (2) In the demethylation with anhydrous aluminum bromide, the 5- and 7-methoxyl groups on 4',5,7-trimethoxy- and 3',4',5,7-tetramethoxy-8-hydroxyflavone were selectively split to give the corresponding 5,7,8-trihydroxyflavones in good yield.However, the demethylation was not accessible to the synthesis of 5,7,8-trihydroxy-3',4',5'-trimethoxyflavone, 4',5,7,8-tetrahydroxy-3'-methoxy-, and 3',5,7,8-tetrahydroxy-4'-methoxyflavone, because of the cleavage of the methoxyl groups on the B ring.The synthesized flavones were employed for the identification of the two natural flavones, which were proposed to be 4',5,8-trihydroxy-7-methoxyflavone and 4',5,8-trihydroxy-3',7-dimethoxyflavone.The former, salvitin, was revised to 4',5,7-trihydroxy-6-methoxyflavone and the latter seemed to be 4',5,7-trihydroxy-3',8-dimethoxyflavone.