41444-33-1 Usage
Description
1-(2-Thienylthio)acetone, also known as tiopronin, is a chemical compound with the molecular formula C6H8OS2. It is a thiol-containing compound characterized by a thione group. Tiopronin is widely recognized for its pharmaceutical applications, particularly in the treatment of cystinuria and nephrolithiasis. As a chelating agent, it can bind to heavy metals, facilitating their removal from the body. Additionally, it has been investigated for its potential antioxidant and anti-inflammatory properties, and it plays a role in the synthesis of various organic compounds and as a reagent in chemical reactions. This versatility positions 1-(2-Thienylthio)acetone as a valuable asset across the medical, pharmaceutical, and chemical industries.
Uses
Used in Pharmaceutical Applications:
1-(2-Thienylthio)acetone is used as a pharmaceutical agent for the treatment of cystinuria and nephrolithiasis, conditions characterized by the formation of kidney stones due to an excess of certain amino acids in the urine. Its chelating properties enable it to bind to these amino acids, reducing their concentration and preventing stone formation.
Used in Heavy Metal Detoxification:
As a chelating agent, 1-(2-Thienylthio)acetone is used for heavy metal detoxification, where it binds to and helps remove heavy metals from the body, mitigating their toxic effects.
Used in Antioxidant and Anti-Inflammatory Research:
1-(2-Thienylthio)acetone is used in research for its potential antioxidant and anti-inflammatory properties, which could contribute to the development of new therapeutic agents for various conditions.
Used in Chemical Synthesis:
In the chemical industry, 1-(2-Thienylthio)acetone is used in the synthesis of various organic compounds, contributing to the creation of new chemical entities with diverse applications.
Used as a Reagent in Chemical Reactions:
1-(2-Thienylthio)acetone serves as a reagent in chemical reactions, facilitating specific transformations and processes in the synthesis of target compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 41444-33-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,4,4 and 4 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 41444-33:
(7*4)+(6*1)+(5*4)+(4*4)+(3*4)+(2*3)+(1*3)=91
91 % 10 = 1
So 41444-33-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H8OS2/c1-6(8)5-10-7-3-2-4-9-7/h2-4H,5H2,1H3
41444-33-1Relevant articles and documents
Substituted α-Sulfur Methyl Carbanions: Effective Homologating Agents for the Chemoselective Preparation of β-Oxo Thioethers from Weinreb Amides
Senatore, Raffaele,Ielo, Laura,Urban, Ernst,Holzer, Wolfgang,Pace, Vittorio
supporting information, p. 2466 - 2470 (2018/05/03)
The proper generation of α-thiomethyllithium reagents via reductive lithiation or deprotonation followed by reaction with variously functionalized Weinreb amides represents an excellent method to access β-oxo thioethers. The procedure is adaptable to alky
SYNTHESIS AND CONFORMATIONAL ANALYSIS OF 2-METHYLTHIO DERIVATIVES OF 1-(2-THIENYL)ETHANOL AND THEIR O-METHYL DERIVATIVES
Fernandez, I.,Llera, J. M.,Zorrilla, F.,Alcudia, F.
, p. 291 - 301 (2007/10/02)
The synthesis and conformational analysis of the title compounds are reported.The conformational properties of the 2-thienyl derivatives, deduced from 1H-nmr and ir data, are compared with those for 2-furyl analogs and the results have been interpreted taking into account the stronger (OH...Ring) intramolecular association in the 2-furyl derivatives.
