4145-94-2

Usage

Uses

Used in Pharmaceutical Industry:
2,4,4-trimethyl-4,5-dihydro-1,3-thiazole is used as a synthetic intermediate for the production of various pharmaceuticals. Its chemical structure allows it to be a key component in the synthesis of drugs, contributing to the development of new medications.
Used in Agrochemical Industry:
In the agrochemical sector, 2,4,4-trimethyl-4,5-dihydro-1,3-thiazole serves as a synthetic intermediate for the creation of agrochemicals. Its role in the synthesis process is essential for producing effective products for agricultural applications.
Used in Specialty Chemicals Production:
2,4,4-trimethyl-4,5-dihydro-1,3-thiazole is utilized as a synthetic intermediate in the production of specialty chemicals. Its versatility in chemical reactions makes it a valuable component in the formulation of various specialty products.
Used in Food Industry:
As a flavoring agent, 2,4,4-trimethyl-4,5-dihydro-1,3-thiazole is used in the food industry to enhance the taste and aroma of certain food products. Its distinct odor plays a role in creating unique flavor profiles.
Used in Perfumery and Personal Care Products:
2,4,4-trimethyl-4,5-dihydro-1,3-thiazole is employed as a fragrance in perfumes and personal care products. Its strong, characteristic scent is an important element in creating appealing scents for consumer products.

Upstream product

• 1569-04-6 1-chloro-2-acetylamino-2-methylpropane 
• 5954-68-7 2-methyl-2-propenethiol 
• 75-05-8 acetonitrile 
• 124-68-5 2-Amino-2-methyl-1-propanol 
• 75-36-5 acetyl chloride 
• 115-11-7 isobutene 
• 14967-17-0 1-mercapto-2-methyl-2-hydroxy-propane 
• 1569-96-6 N-(1-hydroxy-2-methylpropan-2-yl)acetamide 

Downstream Products

• 40052-03-7 N-benzoyl-thioglycine S-{2-methyl-2-[1-(5-oxo-2-phenyl-oxazol-4-ylidene)-ethylamino]-propyl} ester 

Relevant academic research and scientific papers

Generation of cyclic ketene-N,X-acetals (X = O, S) from 2-alkyl-1,3-oxazolines and 2-alkyl-1,3-thiazolines. Reactions with acid chlorides, 1,3-diacid chlorides and N-(chlorocarbonyl) isocyanate

2-Alkyl-1,3-oxazolines, 2-alkyl-1,3-thiazolines, and the corresponding cyclic ketene-N,X-acetals (X = O, S) derived from them were reacted with monoacid chlorides, diacid chlorides, triacid chlorides. A series of these carbon-carbon bond-forming reactions and cyclizations to both substituted 2,3-dihydrooxazolo[3,2-a]pyridine-5,7-diones and 2,3-dihydrothiazolo[3,2-a] pyridine-5,7-diones proceeded under mild reaction conditions. Cyclic ketene-N,X-acetal intermediates play important roles in all these reactions. Related cyclizations with N-(chlorocarbonyl) isocyanate formed substituted 2,3-dihydrooxazolo[3,2-c]pyrimidine-5,7-diones and 2,3-dihydrothiazolo[3,2-c] pyrimidine-5,7-diones. Georg Thieme Verlag Stuttgart.

Reactions of 2-methylthiazolines and N-methyl cyclic ketene-N,S-acetals with acid chlorides

Carbon-carbon bond formation occurs under mild conditions when 2-methylthiazolines react with acid chlorides to form N-acyl-β-keto cyclic ketene-N,S-acetals. N-Methyl cyclic ketene-N,S-acetals, generated from 2-methyl-thiazolines, can react further with acid chlorides to form N-methyl-β-keto cyclic ketene-N,S-acetals.

Research on radioprotective agents: Δ-2 Thiazolines and homologous derivatives

Compounds derived from Δ-2 thiazoline, Δ-2 thiazolinium iodoalkylate and 4,5-dihydro-1,3 thiazine have been prepared and evaluated as potential antiradiation agents in mice. They generally have a low toxicity and significant radioprotective activity.