416864-77-2

Upstream product

• 416864-75-0 (+)-(1R:4R)-trans-Δ²-p-Menthen-9-ol 
• 5113-87-1 3-methyl-6-(prop-1-en-2-yl)cyclohexene 

Downstream Products

• 182699-77-0 (-)-(3aS,3aS,7aR)-3a,4,5,7a-tetrahydro-3,6-dimethylbenzofuran-2(3H)-one 
• 503272-14-8 (R)-2-{(1S,2S,3S,4R)-2-Hydroxy-4-methyl-3-[2-(2-methyl-[1,3]dithiolan-2-yl)-ethyl]-cyclohexyl}-propionic acid methyl ester 
• 503272-16-0 (R)-2-{(1S,3S,4R)-2-[1-Methoxy-meth-(E)-ylidene]-4-methyl-3-[2-(2-methyl-[1,3]dithiolan-2-yl)-ethyl]-cyclohexyl}-propionic acid methyl ester 
• 503272-15-9 (R)-2-{(1S,3S,4R)-4-Methyl-3-[2-(2-methyl-[1,3]dithiolan-2-yl)-ethyl]-2-oxo-cyclohexyl}-propionic acid methyl ester 
• 87322-20-1 (R)-2-[(1S,3S,4R)-2-[1-Methoxy-meth-(Z)-ylidene]-4-methyl-3-(3-oxo-butyl)-cyclohexyl]-propionic acid methyl ester 
• 63968-64-9 C₁₂H₁₃O₂(CH₃)3(O)(OO) 

Relevant academic research and scientific papers

Stereoselective total synthesis of (+)-artemisinin

The total synthesis of the novel antimalarial drug, a sesquiterpene endoperoxide, (+)-artemisinin is described. The approach is flexible and stereoselective. The use of an intermolecular radical reaction on an intermediate iodolactone and a Wittig reaction on a ketone were employed for the synthesis.