41755-68-4Relevant academic research and scientific papers
Photochemical Activation of Aromatic Aldehydes: Synthesis of Amides, Hydroxamic Acids and Esters
Nikitas, Nikolaos F.,Apostolopoulou, Mary K.,Skolia, Elpida,Tsoukaki, Anna,Kokotos, Christoforos G.
supporting information, p. 7915 - 7922 (2021/05/03)
A cheap, facile and metal-free photochemical protocol for the activation of aromatic aldehydes has been developed. Utilizing thioxanthen-9-one as the photocatalyst and cheap household lamps as the light source, a variety of aromatic aldehydes have been activated and subsequently converted in a one-pot reaction into amides, hydroxamic acids and esters in good to high yields. The applicability of this method was highlighted in the synthesis of Moclobemide, a drug against depression and social anxiety. Extended and detailed mechanistic studies have been conducted, in order to determine a plausible mechanism for the reaction.
ORGANIC REACTIONS AT ALUMINA SURFACES. AN EXTREMELY SIMPLE, CONVENIENT AND SELECTIVE METHOD FOR ACETYLATING PRIMARY ALCOHOLS IN THE PRESENCE OF SECONDARY ALCOHOLS.
Posner, Gary H.,Oda, Mitsunori
, p. 5003 - 5006 (2007/10/02)
Stirring primary-secondary diols in ethyl acetate solvent over Woelm alumina leads to the corresponding primary monoacetates simply, conveniently, and in good yields.In this way, primary hydroxyalkylphenols are converted into acetoxyalkylphenols, and primary arylamines are transformed into the corresponding acetamides.
