4209-02-3

Basic information

• Product Name: 1-(4-bromophenyl)-2-chloroethan-1-one
• Synonyms: 1-(4-bromophenyl)-2-chloroethan-1-one;2-Chloro-4’4'-Bromo-2-chloroacetophenone;4'-Bromo-α-chloroacetophenone;2-Chloro-4'-bromoacetophenone;p-Bromo-2-chloroacetophenone
• CAS NO: 4209-02-3
• Molecular Formula: C₈H₆BrClO
• Molecular Weight: 233.48964
• EINECS: 224-134-6
• Mol File: 4209-02-3.mol
• Article Data: 46

Chemical Properties

• Melting Point: 119-120 °C
• Boiling Point: 306.7 °C at 760 mmHg
• Flash Point: 139.3 °C
• Appearance: /
• Density: 1.572 g/cm³
• Vapor Pressure: 0.000759mmHg at 25°C
• Refractive Index: 1.571
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 1-(4-bromophenyl)-2-chloroethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-bromophenyl)-2-chloroethan-1-one(4209-02-3)
• EPA Substance Registry System: 1-(4-bromophenyl)-2-chloroethan-1-one(4209-02-3)

Safety Data

• Hazard Codes: Xn
• Hazardous Substances Data: 4209-02-3(Hazardous Substances Data)

Usage

Uses

2-Chloro-4''-bromoacetophenone

InChI:InChI=1/C8H6BrClO/c9-7-3-1-6(2-4-7)8(11)5-10/h1-4H,5H2

Upstream product

• 99-90-1 para-bromoacetophenone 
• 108-86-1 bromobenzene 
• 79-04-9 chloroacetyl chloride 
• 99-73-0 para-bromophenacyl bromide 
• 5391-88-8 1-(4-bromophenyl)ethanol 
• 766-96-1 4-bromo-1-ethynylbenzene 
• 64-19-7 acetic acid 
• 94783-77-4 Dimethyl-<4-brom-phenacyl>-sulfoniumchlorid 
• 619-41-0 4-(bromoacetyl)toluene 
• 21757-86-8 1-(4-bromophenyl)-2,2,2-trichloroethan-1-ol 
• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 79-11-8 chloroacetic acid 
• 80-11-5 N-methyl-N-nitrosotoluene-p-sulfonamide 

Downstream Products

• 586-76-5 4-Bromobenzoic acid 
• 58881-56-4 2,2'-thiobis[1-(4-bromophenyl)ethanone] 
• 81585-72-0 1-(4-bromo-phenyl)-2-iodo-ethanone 
• 61592-47-0 1-(4-bromophenyl)-2-chloroethan-1-ol 
• 59031-97-9 α-chloromethyl p-bromophenyl ketoxime 
• 111824-69-2 (4-bromo-phenyl)-(4,8-dimethoxy-3-methyl-benzo[1,2-b;5,4-b']difuran-2-yl)-ketone 
• 61378-99-2 6-(4-bromo-phenyl)-2,3-dihydro-[1,4]oxathiin 
• 111780-43-9 2,4-bis(4-bromobenzoylmethylthio)pyrimidine 
• 119730-32-4 4-amino-2-(4-bromobenzoylmethylthio)pyrimidin-6(1H)-one 
• 3343-45-1 4-bromo-2-hydroxyacetophenone 
• 57265-17-5 1-(p-bromobenzoylmethyl)-3-[2,4-dichloro-β-(2,4-dichlorobenzyloxy)phenethyl]imidazolium chloride 
• 1240914-03-7 4-{(1S, 2S)-2-[((R)-4-cyclobutyl-2-methylpiperazin-1-yl)carbonyl]-cyclopropyl}-benzamide 
• 1240914-95-7 ((1S,2S)-2-(4-bromophenyl)cyclopropyl)((R)-4-cyclobutyl-2-methylpiperazin-1-yl)methanone 
• 1240914-98-0 4-((1S, 2S)-2-((R)-4-cyclobutyl-2-methylpiperazine-1-carbonyl)cyclopropyl)benzonitrile 

Relevant articles and documents

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A practical synthesis of α-bromo/iodo/chloroketones from olefins under visible-light irradiation conditions

A practical synthesis of α-bromo/iodo/chloroketones from olefins under visible-light irradiation conditions has been developed. In the presence of PhI(OAc)2 as promoter and under ambient conditions, the reactions of styrenes and triiodomethane undergo the transformation smoothly to deliver the corresponding α-iodoketones without additional photocatalyst in good yields under sunlight irradiation. Meanwhile, the reactions of styrenes with tribromomethane and trichloromethane generate the desired α-bromoketones and α-chloroketones in high yields by using Ru(bpy)3Cl2 as a photocatalyst under blue LED (450–455 nm) irradiation.

Preparation method of aituomode

The invention discloses a preparation method of aituomode. Bromo-benzene is used as an initial raw material to prepare aituomode by adopting a convergent synthesis route. The yield of the preparationmethod is high, the cost is low, the amount of generated waste water, waste gas, and waste solids is low, the operation is convenient, and the application value is high.