4210-82-6

Usage

Compound Type

Phenolic and heterocyclic

Ring Structure

Contains a pyridine and oxazole ring

Applications

Pharmaceutical: Used in pharmaceutical and research applications
Biological Activities: Potential biological activities and therapeutic properties
Antioxidant: Exhibits antioxidant properties
Anti-inflammatory: Shows anti-inflammatory properties

Potential Uses

Disease Treatment: Studied for its potential use in treating various diseases and conditions
Organic Synthesis: Utilized in various organic synthesis reactions due to its unique structure and reactivity

InChI:InChI=1/C14H10N2O2/c17-12-5-3-10(4-6-12)13-9-16-14(18-13)11-2-1-7-15-8-11/h1-9,17H

Upstream product

• 4195-29-3 3-[5-(4-benzyloxy-phenyl)-oxazol-2-yl]-pyridine 
• 99906-16-8 3-{5-[4-(2,3-dihydroxy-3-methyl-butoxy)-phenyl]-oxazol-2-yl}-1-methyl-pyridinium; chloride 
• 3731-52-0 3-Aminomethylpyridine 
• 2491-38-5 2-bromo-1-(4'-hydroxyphenyl)-1-ethanone 
• 33864-03-8 O-methylhalfordinol 
• 123-11-5 4-methoxy-benzaldehyde 
• 4195-27-1 N-[2-(4-benzyloxy-phenyl)-2-oxo-ethyl]-nicotinamide 
• 4674-98-0 2-methyl-4-[4-(2-pyridin-3-yl-oxazol-5-yl)-phenoxy]-butane-2,3-diol 

Downstream Products

• 33864-03-8 O-methylhalfordinol 
• 33864-02-7 1-acetoxy-4-(2-pyridin-3-yl-oxazol-5-yl)-benzene 
• 34433-51-7 3-[5-(4-hydroxy-phenyl)-oxazol-2-yl]-1-methyl-pyridinium; iodide 
• 17190-80-6 5-(4-[(3-methylbut-2-en-1-yl)oxy]phenyl)-2-(pyridin-3-yl)oxazole 
• 89764-17-0 (E)-5-(4-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]phenyl)-2-(pyridin-3-yl)oxazole 
• 34433-52-8 5-[5-(4-methoxy-phenyl)-oxazol-2-yl]-1-methyl-pyridinium; iodide 

Relevant academic research and scientific papers

Structure-Activity Relationships of New Natural Product-Based Diaryloxazoles with Selective Activity against Androgen Receptor-Positive Breast Cancer Cells

Targeted therapies for ER+/PR+ and HER2-amplified breast cancers have improved patient survival, but there are no therapies for triple negative breast cancers (TNBC) that lack expression of estrogen and progesterone receptors (ER/PR), or amplification or

Practical oxazole synthesis mediated by iodine from α-bromoketones and benzylamine derivatives

The reagent system of I2/K2CO3 could efficiently promote the oxazole synthesis from α-bromoketones and benzylamine derivatives in DMF. This method was not only suitable for 2,5-diaryl oxazole synthesis but also for 2,4,5-trisubstituted oxazole and 5-alkyl/alkenyl oxazole synthesis. Furthermore, this method was successfully applied to a one-step synthesis of a natural product halfordinol in 62% yield.