4214-78-2

Usage

Uses

Used in Pharmaceutical Industry:
5-Chloro-1-Methylpyridin-2-one is used as a key intermediate in the synthesis of pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications, contributing to advancements in medicine.
Used in Agrochemical Production:
In the agrochemical sector, 5-Chloro-1-Methylpyridin-2-one serves as an intermediate for the production of pesticides, herbicides, and other related products. Its incorporation into these chemicals aids in the development of effective solutions for pest and weed control, thereby supporting agricultural productivity and crop protection.
It is crucial to handle 5-Chloro-1-Methylpyridin-2-one with care due to its potential hazards if not properly managed, ensuring safety in its applications across various industries.

Upstream product

• 4214-79-3 5-chloro-2-pyridinol 
• 74-88-4 methyl iodide 
• 16110-09-1 2,5 dichloropyridine 
• 421-20-5 Methyl fluorosulfonate 
• 4214-79-3 5-chloro-1,2-dihydropyridin-2-one 

Downstream Products

• 112423-14-0 4-methoxy-1-methyl-3-phenylpyridin-2(1H)-one 
• 16110-09-1 2,5 dichloropyridine 

Relevant academic research and scientific papers

Light-induced [2 + 2] cycloadditions for the construction of cyclobutane-fused pyridinyl sulfonyl fluorides

Cyclobutanes are an important class of motifs present in a wide range of natural products and other biologically significant molecules. A photocatalytic [2 + 2] cycloaddition between pyridones or isoquinolones and ethenesulfonyl fluoride was achieved, providing a portal to a class of unique cyclobutane-fused pyridinyl sulfonyl fluorides with quaternary rigid rings (30 examples). Further applications of these novel sulfonyl fluoride molecules in SuFEx click chemistry were also accomplished, providing the corresponding sulfonates and sulphonamides with reasonable yields.

ACLY INHIBITORS AND USES THEREOF

The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.

Iron-catalyzed regioselective direct arylation at the C-3 position of N-alkyl-2-pyridone

A number of pharmaceutical compounds possess an arylated 2-pyridone moiety. The existing reports using expensive starting materials and/or superstoichiometric metal salts have prompted us to explore a possible user-friendly method for their synthesis. In this report, we demonstrate an easy-to-handle reaction condition with an iron catalyst for the exclusive generation of C-3-arylated pyridone via C-H functionalization.

Polyhalogenoaromatic Compounds. Part 42. 13C N.m.r. Spectra of Polyhalogeno-pyridines and pyrimidines

13C N.m.r. spectra are reported for a number of polyhaloheno-pyridines and -pyrimidines.Substituent effects have been calculated and the results used to assign structures.