42152-99-8

Basic information

• Product Name: 2-(4-CHLORO-BUTYL)-ISOINDOLE-1,3-DIONE
• Synonyms: 2-(4-CHLORO-BUTYL)-ISOINDOLE-1,3-DIONE;2-(4-chlorobutyl)isoindoline-1,3-dione
• CAS NO: 42152-99-8
• Molecular Formula: C₁₂H₁₂ClNO₂
• Molecular Weight: 237.68218
• Mol File: 42152-99-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 365.7±25.0 °C(Predicted)
• Appearance: /
• Density: 1.287±0.06 g/cm3(Predicted)
• PKA: -2.14±0.20(Predicted)
• CAS DataBase Reference: 2-(4-CHLORO-BUTYL)-ISOINDOLE-1,3-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-CHLORO-BUTYL)-ISOINDOLE-1,3-DIONE(42152-99-8)
• EPA Substance Registry System: 2-(4-CHLORO-BUTYL)-ISOINDOLE-1,3-DIONE(42152-99-8)

Safety Data

• Hazardous Substances Data: 42152-99-8(Hazardous Substances Data)

Usage

Chemical family

Isoindole-1,3-dione
Belonging to a group of synthetic organic compounds characterized by a specific chemical structure and properties.

Chloro-butyl group

4-chloro-butyl
A functional group consisting of a 4-carbon chain with a chlorine atom attached, connected to the isoindole-1,3-dione ring.

Structural features

The compound has a unique structure that includes a fused isoindole ring and a 1,3-dione moiety, which may contribute to its potential biological activities.

Potential applications

Medicinal chemistry and pharmaceuticals
Due to its structural features and possible biological activities, the compound may have uses in the development of new drugs and therapies.

Further research needed

Properties and potential uses
More studies and research are required to fully understand the properties, biological activities, and potential applications of 2-(4-chloro-butyl)-isoindole-1,3-dione.

Upstream product

• 6940-78-9 4-chlorobutyl bromide 
• 1074-82-4 potassium phtalimide 
• 110-56-5 1,4-dichlorobutane 
• 3481-09-2 N-chlorophthalimide 
• 5394-18-3 2-(4-bromobutyl)isoindoline-1,3-dione 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 6821-01-8 2-(4-(piperidin-1-yl)butyl)isoindoline-1,3-dione 

Downstream Products

• 66917-06-4 N-(4-azidobutyl)phthalimide 
• 136743-89-0 3-(2-Chloro-phenyl)-1-[4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-5,7-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-quinazoline-6-carboxylic acid ethyl ester 
• 5457-30-7 4-phthalimido-1-iodobutane 
• 123-75-1 pyrrolidine 
• 550-44-7 N-methylphthalimide 

Relevant articles and documents

A NOVEL SYNTHETIC PATHWAY TOWARDS SOLITHROMYCIN AND PURIFICATION THEREOF

The present invention relates to an efficient route of synthesis of solithromycin and to a method of its purification which obviates the necessity of chromatographic purifications and improves the quality of the product by efficiently removing impurities.

Identification of a gene cluster that directs putrebactin biosynthesis in Shewanella species: PubC catalyzes cyclodimerization of N-Hydroxy-N- succinylputrescine

Putrebactin is a dihydroxamate iron chelator produced by the metabolically versatile marine bacterium Shewanella putrefaciens. It is a macrocyclic dimer of N-hydroxy-N-succinyl-putrescine (HSP) and is structurally related to desferrioxamine E, which is a

Tests of a Piperidino Mask for the Protection of Functionalized Carbon Sites in Multistep Syntheses

Primary alkyl chlorides (R-Cl) are easily isolated in excellent yield after treatment of the appropriate N-alkylpiperidines (R-NC5H10) with α-chloroethyl chloroformate.The method is exemplified by the conversion of a variety of alkylpiperidines, including systems with other sensitive functionalities, to the respective chlorides in yields varying from 90 to 97percent.The potential significance of this process in drug congener preparation and in total synthesis is outlined.Similar fragmentations of N-sec-alkylpiperidines are described.