5457-30-7

Basic information

• Product Name: 2-(4-iodobutyl)isoindole-1,3-dione
• Synonyms: 2-(4-iodobutyl)isoindole-1,3-dione;2-(4-Iodobutyl) isoindoline-1,3-dione
• CAS NO: 5457-30-7
• Molecular Formula: C₁₂H₁₂INO₂
• Molecular Weight: 329.14
• Mol File: 5457-30-7.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 389.3°C at 760 mmHg
• Flash Point: 189.2°C
• Appearance: /
• Density: 1.714g/cm³
• Vapor Pressure: 2.88E-06mmHg at 25°C
• Refractive Index: 1.64
• CAS DataBase Reference: 2-(4-iodobutyl)isoindole-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-iodobutyl)isoindole-1,3-dione(5457-30-7)
• EPA Substance Registry System: 2-(4-iodobutyl)isoindole-1,3-dione(5457-30-7)

Safety Data

• Hazardous Substances Data: 5457-30-7(Hazardous Substances Data)

Usage

Chemical structure

2-(4-iodobutyl)isoindole-1,3-dione is an isoindole-1,3-dione derivative with a 4-iodobutyl substituent.

Usage

It is commonly used in research and pharmaceutical applications as a building block in the synthesis of complex organic molecules and pharmaceutical intermediates.

Biological activities

It has been studied for its potential antimicrobial, antitumor, and anti-inflammatory properties.

Importance of the 4-iodobutyl group

The 4-iodobutyl group on the isoindole-1,3-dione scaffold is crucial in modulating the compound's reactivity and binding affinity to biological targets.

Value in research

2-(4-iodobutyl)isoindole-1,3-dione is a valuable molecule with diverse potential applications in the field of chemistry and pharmaceutical research.

InChI:InChI=1/C12H12INO2/c13-7-3-4-8-14-11(15)9-5-1-2-6-10(9)12(14)16/h1-2,5-6H,3-4,7-8H2

Upstream product

• 85-44-9 phthalic anhydride 
• 24697-70-9 N-(4-hydroxybutyl)phthalimide 
• 1074-82-4 potassium phtalimide 
• 86101-33-9 N-<(4-(N-nitroso-p-toluenesulfonamido)-1-butyl)>phthalimide 
• 35517-18-1 N-(4-amino-1-butyl)phthalimide hydrochloride 
• 3184-61-0 4-phthalimidobutyronitrile 
• 5460-29-7 2-(3-bromopropyl)isoindole-1,3-dione 
• 15544-49-7 N-(N⁴-p-toluenesulfonyl)-4-aminobutylphthalimide 
• 136918-14-4 phthalimide 
• 86088-65-5 N-(4-hydroxy-1-butyl)phthalimide tosylate 
• 5394-18-3 2-(4-bromobutyl)isoindoline-1,3-dione 
• 42152-99-8 2-(4-chlorobutyl)isoindoline-1,3-dione 
• 628-21-7 1,4-Diiodobutane 

Downstream Products

• 111656-41-8 DL-α-Methyllysin 
• 70-54-2 2,6-diaminocaproic acid 
• 875681-02-0 (S)-N¹-phthaloyl-N⁵-(o-nitrophenylsulfonyl)-N⁸-(tert-butyloxycarbonyl)-1,8-diamino-5-azanonane 
• 875680-91-4 (R)-N¹-phthaloyl-N⁵-(o-nitrophenylsulfonyl)-N⁸-(tert-butyloxycarbonyl)-1,8-diamino-5-azanonane 
• 1111643-48-1 2-(4-{[3-(ethyl(2-nitrobenzenesulfonyl)amino)propyl](2-nitrobenzenesulfonyl)amino}butyl)isoindole-1,3-dione 
• 1111643-95-8 2-(4-{[3-(ethyl(2-nitrobenzenesulfonyl)amino)-1,1-(2H)2-propyl](2-nitrobenzenesulfonyl)amino}butyl)isoindole-1,3-dione 
• 1111643-96-9 2-(4-{[3-(ethyl(2-nitrobenzenesulfonyl)amino)-1,1,2,2-⁽²⁾H₄-propyl](2-nitrobenzenesulfonyl)amino}butyl)isoindole-1,3-dione 
• 1111643-97-0 2-(4-{[3-(benzyl(2-nitrobenzenesulfonyl)amino)propyl](2-nitrobenzenesulfonyl)amino}butyl)isoindole-1,3-dione 
• 1111643-98-1 2-(4-{[3-(benzyl(2-nitrobenzenesulfonyl)amino)-1,1-⁽²⁾H₂-propyl](2-nitrobenzenesulfonyl)amino}butyl)isoindole-1,3-dione 
• 1111644-00-8 2-(4-{[3-(isopropyl(2-nitrobenzenesulfonyl)amino)propyl](2-nitrobenzenesulfonyl)amino}butyl)isoindole-1,3-dione 
• 1111644-01-9 2-(4-{[3-(cyclohexyl(2-nitrobenzenesulfonyl)amino)propyl](2-nitrobenzenesulfonyl)amino}butyl)isoindole-1,3-dione 
• 15102-28-0 5-(1,3-dioxoisoindolin-2-yl)pentanenitrile 
• 132751-72-5 2-{4-[5-Methoxy-2-(4-methoxy-phenyl)-3-methyl-indol-1-yl]-butyl}-isoindole-1,3-dione 
• 1165802-14-1 C₄₁H₃₆N₂O₄ 

Relevant articles and documents

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Copper-Catalyzed Regioselective Borocarbonylative Coupling of Unactivated Alkenes with Alkyl Halides: Synthesis of β-Boryl Ketones

The borocarbonylative coupling of unactivated alkenes with alkyl halides remains a challenge. In this communication, a Cu-catalyzed borocarbonylative coupling of unactivated alkenes with alkyl halides for the synthesis of β-boryl ketones has been developed. A broad range of β-boryl ketone derivatives was prepared in moderate to excellent yields with complete regioselectivity.

IRAK DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.