42239-38-3

Upstream product

• 42239-63-4 2-aminophenyl-(thien-2-yl)methanone 
• 50817-56-6 [2]thienyl-[2-(toluene-4-sulfonylamino)-phenyl]-ketone 
• 42840-02-8 2-(Toluene-4-sulfonylamino)-benzoyl chloride 

Downstream Products

• 22874-60-8 2-(isocyanatobenzyl)thiophene 
• 372109-32-5 1-(2-thiophen-2-ylmethyl-phenyl)-piperidine-2,6-dione 
• 372109-37-0 5-hydroxy-1-(2-thiophen-2-ylmethyl-phenyl)-pyrrolidin-2-one 
• 372109-38-1 6-hydroxy-1-(2-thiophen-2-ylmethyl-phenyl)-piperidin-2-one 
• 23006-40-8 2-<2-(4-methylpiperazin-1-yl-carboxamido)benzyl>thiophene 

Relevant academic research and scientific papers

Process for making 11-piperazino-diazepines, oxazepines, thiazepines and azepines

This invention concerns a novel process for the preparation of 6-piperazinyl derivatives of morphantridine and corresponding ring-substituted and hereto analogues thereof, comprising reacting a compound of the formula: SPC1 Wherein A is benzene or thiophene, and X is --CH2 -- or a hetero atom or group, with a complex comprising titanium, zirconium, hafnium or vanadium and a corresponding piperazinyl derivative. The end products are in general known and useful as neuroleptics.