50817-56-6

Basic information

• Product Name: [2]thienyl-[2-(toluene-4-sulfonylamino)-phenyl]-ketone
• Synonyms: [2]thienyl-[2-(toluene-4-sulfonylamino)-phenyl]-ketone
• CAS NO: 50817-56-6
• Molecular Weight: 357.454
• Mol File: 50817-56-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [2]thienyl-[2-(toluene-4-sulfonylamino)-phenyl]-ketone(CAS DataBase Reference)
• NIST Chemistry Reference: [2]thienyl-[2-(toluene-4-sulfonylamino)-phenyl]-ketone(50817-56-6)
• EPA Substance Registry System: [2]thienyl-[2-(toluene-4-sulfonylamino)-phenyl]-ketone(50817-56-6)

Safety Data

• Hazardous Substances Data: 50817-56-6(Hazardous Substances Data)

Upstream product

• 6311-23-5 2-(toluene-4-sulfonylamino)-benzoic acid 
• 42239-63-4 2-aminophenyl-(thien-2-yl)methanone 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1388038-78-5 2-(phenylethynyl)-3-(thiophen-2-yl)-1-tosyl-1H-indole 
• 1315477-51-0 N-(2-(1-hydroxy-1-(thiophen-2-yl)prop-2-yn-1-yl)phenyl)-4-methylbenzenesulfonamide 
• 20409-64-7 (2-hydroxyphenyl)(thiophen-2-yl)methanone 
• 23006-40-8 2-<2-(4-methylpiperazin-1-yl-carboxamido)benzyl>thiophene 
• 22874-60-8 2-(isocyanatobenzyl)thiophene 
• 42239-38-3 2-(2-aminobenzyl)-thiophene 
• 42239-63-4 2-aminophenyl-(thien-2-yl)methanone 

Relevant articles and documents

Silver triflate catalyzed tandem heterocyclization/alkynylation of 1-((2-tosylamino)aryl)but-2-yne-1,4-diols to 2-alkynyl indoles

Don't cross me! 2-Alkynyl indoles were prepared efficiently by the AgOTf-catalyzed tandem heterocyclization/alkynylation of 1-(2-tosylamino)aryl) but-2-yne-1,4-diols under mild conditions (see scheme). The attractiveness of this approach lies in the fact that both the indole ring and alkyne side chain of the N-heterocycle are sequentially formed from low cost, readily available, and ecologically benign starting materials. It also provides the first route to this synthetically valuable class of compounds that is not based on a cross-coupling strategy. Copyright