42353-58-2

Basic information

• Product Name: 1-(1,2-diphenyl-vinyl)-pyrrolidine
• Synonyms: 1-(1,2-diphenyl-vinyl)-pyrrolidine
• CAS NO: 42353-58-2
• Molecular Weight: 249.356
• Mol File: 42353-58-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(1,2-diphenyl-vinyl)-pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1,2-diphenyl-vinyl)-pyrrolidine(42353-58-2)
• EPA Substance Registry System: 1-(1,2-diphenyl-vinyl)-pyrrolidine(42353-58-2)

Safety Data

• Hazardous Substances Data: 42353-58-2(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 451-40-1 phenyl benzyl ketone 
• 501-65-5 diphenyl acetylene 

Downstream Products

• 37928-17-9 5-methyl-3,4-diphenyl isoxazole 
• 181695-72-7 valdecoxib 
• 198470-84-7 parecoxib 
• 181696-73-1 3,4-diphenyl-4-hydrido-5-hydroxy-5-methylisoxazole 
• 1779-91-5 1,2-diphenyl-2-(pyridin-2-yl)ethan-1-one 
• 720-43-4 2-fluoro-1,2-diphenylethanone 
• 365-01-5 2,2-difluoro-2-phenylacetophenone 
• 5533-73-3 4,5-Diphenyl-1H-[1,2,3]triazole 
• 88875-34-7 [1-Phenyl-1-pyrrolidin-1-yl-meth-(Z)-ylidene]-phosphoramidic acid diphenyl ester 
• 94191-34-1 [2,2-Diphenyl-1-pyrrolidin-1-yl-eth-(Z)-ylidene]-phosphoramidic acid diphenyl ester 
• 95867-96-2 3,4,5-triphenyl-5-pyrrolidin-1-yl-4,5-dihydro-isoxazole 
• 55436-11-8 2-(dimethylaminothiocarbonylthio)desoxybenzoin 

Relevant articles and documents

A process for the preparation of sodium compound handkerchief auspicious past cloth and wherein the intermediate impurity, preparation method and application

The invention provides parecoxib sodium which is prepared by controlling an intermediate impurity and in particular provides a preparation method of a parecoxib sodium compound as well as the intermediate impurity and an application of the parecoxib sodium compound. According to the preparation method provided by the invention, 3-methyl-4,5-diphenyl-4,5-dihydro-isoxazole-5-alcohol is used as an isomer impurity for preparing 5-methyl-3,4-diphenyl-4,5-dihydro-isoxazole-5-alcohol as an intermediate of the parecoxib sodium, the quality of the 3-methyl-4,5-diphenyl-4,5-dihydro-isoxazole-5-alcohol is controlled in the preparation of the parecoxib sodium, specifically, the impurity content is required not to be higher than 0.5 percent, and an important significance is provided for the product quality of the parecoxib sodium; by obtaining the 3-methyl-4,5-diphenyl-4,5-dihydro-isoxazole-5-alcohol as an isomer impurity of the important 5-methyl-3,4-diphenyl-4,5-dihydro-isoxazole-5-alcohol and further studying 3-methyl-4,5-diphenyl-4,5-dihydro-isoxazole-5-alcohol in the aspects of preparation process, detection process and purification process, important quality monitoring significance is provided for the process with the 5-methyl-3,4-diphenyl-4,5-dihydro-isoxazole-5-alcohol as an industrial production raw material.

NOVEL CATALYSTS

The present invention provides novel compounds and ligands that are useful in transition metal catalyzed cross-coupling reactions. For example, the compounds and ligands of the present invention are useful in palladium or gold catalyzed cross-coupling reactions.