4237-00-7

Basic information

• Product Name: O,O-dimethyl S-phenyl phosphorothioate
• Synonyms: Dimethyl phenyl thiophosphate
• CAS NO: 4237-00-7
• Molecular Formula: C₈H₁₁O₃PS
• Molecular Weight: 218.2099
• Mol File: 4237-00-7.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 283.2°C at 760 mmHg
• Flash Point: 125.1°C
• Density: 1.24g/cm³
• Vapor Pressure: 0.00548mmHg at 25°C
• Refractive Index: 1.529
• CAS DataBase Reference: O,O-dimethyl S-phenyl phosphorothioate(CAS DataBase Reference)
• NIST Chemistry Reference: O,O-dimethyl S-phenyl phosphorothioate(4237-00-7)
• EPA Substance Registry System: O,O-dimethyl S-phenyl phosphorothioate(4237-00-7)

Safety Data

• Hazardous Substances Data: 4237-00-7(Hazardous Substances Data)

Upstream product

• 931-59-9 benzenesulfenyl chloride 
• 121-45-9 phosphorous acid trimethyl ester 
• 108-98-5 thiophenol 
• 96-36-6 methyl phosphite 
• 882-33-7 diphenyldisulfane 
• 868-85-9 Dimethyl phosphite 
• 62-53-3 aniline 
• 66003-76-7 Diphenyliodonium triflate 
• 369-57-3 benzenediazonium tetrafluoroborate 
• 813-77-4 Dimethyl chlorophosphate 
• 14204-27-4 N-phenylthiophthalimide 
• 14204-24-1 N-(phenylthio)succinimide 
• 4837-31-4 4-Phenylsulfanyl-morpholine 
• 22946-71-0 Thiophosphorous acid O,O'-dimethyl ester S-phenyl ester 

Downstream Products

• 10258-67-0 (dimethoxythiophosphinoylmercapto)benzene 
• 672-36-6 phenylsulphur trifluoride 
• 74321-39-4 phenylsulfur(VI) trifluoridoxide 
• 203126-16-3 phenyltetrafluoro-λ⁶-sulfanyl chloride 
• 25723-73-3 C₁₂H₂₃O₃PSSi₂ 

Relevant articles and documents

A green and efficient route for P ? S ? C bond construction using copper ferrite nanoparticles as catalyst: a TD-DFT study

Magnetic nanoparticles of CuFe2O4 were applied as catalyst system for one-pot thiophosphate synthesis via the reaction of aryl sulfonyl chlorides with H-phosphonates under conventional heating conditions. This is an extremely efficient and green method for thiophosphate synthesis under base- and solvent-free conditions. Various thiophosphates were obtained in good to excellent yields under the optimized reaction conditions in a short time. The catalyst can be easily recycled from the reaction by an external magnetic field and reused for the next run. In this study, TD-DFT B3LYP/6-31 + G(d) calculations are in good accord with the experimental results. A comparison between experimental and theoretical UV-vis absorption spectra of the thiophosphate 3k has been carried out; and a small hypsochromic shift (only ～ 2 nm) was displayed at maximum absorption. The aim of this work is to investigate the best method and basis set for thiophosphate compounds; therefore, predictions for these compounds can be performed in theoretical studies.

Magnetically recyclable Cu-BTC@Fe3O4 composite-catalyzed C(aryl)-S-P bond formation using aniline, P(O)H compounds and sulfur powder

A Cu-BTC@Fe3O4 composite was prepared and exhibited good catalytic activity toward the synthesis of S-aryl phosphorothioates. The three-component reaction involved the coupling of in situ generated aryl diazonium salts from aniline, R2P(O)H, and sulfur powder, allowing the facile and direct formation of C(aryl)-S-P bonds. A broad scope of substrates survived the reaction conditions to afford the corresponding products in good to excellent yields. Moreover, this heterogeneous catalyst could be magnetically recovered and reused without significant loss of its activity after six cycles.

Synthesis of S-Aryl Phosphorothioates by Copper-Catalyzed Phosphorothiolation of Diaryliodonium and Arenediazonium Salts

Green methods for the synthesis of S-aryl phosphorothioates have been developed based on copper-catalyzed multicomponent reactions involving diaryliodonium/arenediazonium salts, elemental sulfur, and R2P(O)H compounds. Most target products are obtained with these two methods in good to high yields at room temperature. These transformations allow the direct formation P-S and C-S bonds in one reaction.