4245-35-6

Usage

Uses

Used in Perfumery and Personal Care Products:
Acrylic acid isoamyl ester is used as a fragrance ingredient for its fruity, apple-like odor, adding a pleasant scent to perfumes and personal care products.
Used in Food and Beverage Flavorings:
This ester is used as a flavoring agent in the food and beverage industry to impart a fruity taste, enhancing the overall flavor profile of various products.
Used in Industrial Applications:
Acrylic acid isoamyl ester is used as a solvent in various industrial applications, such as inks, adhesives, and coatings, due to its solvent properties and compatibility with different materials.
Used in the Production Process:
Acrylic acid isoamyl ester is produced through the esterification of acrylic acid with isoamyl alcohol, resulting in a compound with a high boiling point and low volatility, suitable for various applications.
It is important to handle acrylic acid isoamyl ester with care due to its potential irritant and flammable properties, ensuring safety in its use across different industries.

InChI:InChI=1/C8H14O2/c1-4-8(9)10-6-5-7(2)3/h4,7H,1,5-6H2,2-3H3

Upstream product

• 123-51-3 i-Amyl alcohol 
• 814-68-6 acryloyl chloride 
• 100983-12-8 3-bromo-propionic acid isopentyl ester 
• 91-66-7 N,N-diethylaniline 
• 62108-70-7 3-chloro-propionic acid isopentyl ester 
• 79-10-7 acrylic acid 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 80758-77-6 bicyclo<2.2.1>hept-5-en-2-carbonsaeure-3-methylbutylester 
• 71617-10-2 isoamyl 4-methoxycinnamate 
• 132876-40-5 1-[2-(3-Methyl-butoxycarbonyl)-ethyl]-4-(phenyl-propionyl-amino)-piperidine-4-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Rational Design of Single-Chain Polymeric Nanoparticles That Kill Planktonic and Biofilm Bacteria

Infections caused by multidrug-resistant bacteria are on the rise and, therefore, new antimicrobial agents are required to prevent the onset of a postantibiotic era. In this study, we develop new antimicrobial compounds in the form of single-chain polymeric nanoparticles (SCPNs) that exhibit excellent antimicrobial activity against Gram-negative bacteria (e.g., Pseudomonas aeruginosa) at micromolar concentrations (e.g., 1.4 μM) and remarkably kill ≥99.99% of both planktonic cells and biofilm within an hour. Linear random copolymers, which comprise oligoethylene glycol (OEG), hydrophobic, and amine groups, undergo self-folding in aqueous systems due to intramolecular hydrophobic interactions to yield these SCPNs. By systematically varying the hydrophobicity of the polymer, we can tune the extent of cell membrane wall disruption, which in turn governs the antimicrobial activity and rate of resistance acquisition in bacteria. We also show that the incorporation of OEG groups into the polymer design is essential in preventing complexation with proteins in biological medium, thereby maintaining the antimicrobial efficacy of the compound even in in vivo mimicking conditions. In comparison to the last-resort antibiotic colistin, our lead agents have a higher therapeutic index (by ca. 2-3 times) and hence better biocompatibility. We believe that the SCPNs developed here have potential for clinical applications and the information pertaining to their structure-activity relationship will be valuable toward the general design of synthetic antimicrobial (macro)molecules.