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Propyl thiocyanate, with the chemical formula C4H7NS, is a colorless liquid characterized by a pungent odor. It is a naturally occurring compound found in foods like mustard and cruciferous vegetables, known for its role as a flavoring agent and its presence in the production of pharmaceuticals. Beyond its use in food and pharmaceuticals, propyl thiocyanate has garnered interest for its potential health benefits, such as antioxidant properties and possible anticancer effects.

4251-16-5

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4251-16-5 Usage

Uses

Used in Flavoring Industry:
Propyl thiocyanate is used as a flavoring agent for enhancing the taste of various food products, capitalizing on its naturally pungent aroma derived from its presence in certain foods.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, propyl thiocyanate serves as a key compound in the production of medications, leveraging its chemical properties for the development of new drugs.
Used in Antioxidant Applications:
Propyl thiocyanate is studied for its potential antioxidant properties, which could contribute to health and wellness by combating oxidative stress and related conditions.
Used in Anticancer Research:
Propyl thiocyanate is also under investigation for its possible anticancer effects, suggesting that it might play a role in cancer prevention or treatment strategies in the future.

Check Digit Verification of cas no

The CAS Registry Mumber 4251-16-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,5 and 1 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4251-16:
(6*4)+(5*2)+(4*5)+(3*1)+(2*1)+(1*6)=65
65 % 10 = 5
So 4251-16-5 is a valid CAS Registry Number.
InChI:InChI=1/C4H7NS/c1-2-3-6-4-5/h2-3H2,1H3

4251-16-5Relevant academic research and scientific papers

A new synthesis of alkane and polyfluoroalkanesulfonyl chlorides

Benfodda, Zohra,Guillen, Franck,Arnion, Helene,Dahmani, Abdelkader,Blancou, Hubert

experimental part, p. 355 - 361 (2010/07/16)

This study describes a new and advantageous procedure for the synthesis of alkanesulfonyl chlorides (2) by the reaction of alkyl thiocyanates (1) with sulfuryl chloride in a mixture of acetic acid and water. The alkanesulfonyl chlorides were obtained in good yields.

2-Hydroxy-N,N,N-tributylethanaminium thiocyanate as solvent and reagent for the preparation of alkyl thiocyanates

Mohanazadeh, Farajollah,Aghvami, Magid

, p. 7240 - 7242 (2008/03/11)

2-Hydroxy-N,N,N-tributylethanaminium thiocyanate was utilized as both solvent and reagent for the conversion of alkyl halides to the corresponding alkyl thiocyanates in good yields under mild conditions.

SYNTHESIS OF ISOTHIOCYANATOPHOSPHORANES AND ISOTHIOCYANATOPHOSPHONIUM SALTS VIA OXIDATIVE ADDITION OF THIOCYANOGEN AND LIGAND SUBSTITUTION. NOVEL REAGENTS FOR CONVERTING HYDROXY GROUPS INTO THIOCYANATE AND ISOTHIOCYANATE FUNCTIONS UNDER MILD CONDITIONS

Burski, J.,Kieszkowski, J.,Michalski, J.,Pakulski, M.,Skowronska, A.

, p. 4175 - 4182 (2007/10/02)

The oxidative addition of thiocyanogen to triphenilphosphine has been investigated by (31)P NMR spectroscopy showing the formation of the isothiocyanatophosphonium salt 8.The analogous reaction between thiocyanogen and alkyl o-phenylene phosphites 7 leads to diisothiocyanatophosphoranes 9.The same products were prepared via ligand substitution from the corresponding chlorophosphonium salt 12 and alkyldichloro-o-phenylene phosphoranes 13 by the action of potassium thiocyanate in the presence of 18-crown-6-ether or more conveniently using lead thiocyanate.The phosphonium salt 8 and phosphoranes 9 were employed as convenient novel reagents for converting hydroxy groups into thiocyanate and isothiocyanate function with high stereoselectivity under very mild conditions.The efficient synthesis of acylisothiocyanates RCONCS,R2P(O)NCS and R2P(S)NCS via addition of thiocyanogen to mixed anhydrides is of special interest.

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