42518-06-9

Basic information

• Product Name: 4-AMIDINOPYRIDINIUM CHLORIDE
• Synonyms: PYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE;4-AMIDINOPYRIDINE HYDROCHLORIDE;4-AMIDINOPYRIDINIUM CHLORIDE;4-AMIDINOPYRIDINIUM HYDROCHLORIDE;4-PYRIDINECARBOXIMIDAMIDE, HYDROCHLORIDE;ISONICOTINAMIDINE HYDROCHLORIDE;BUTTPARK 32\03-56;Isonicotinimidamide hydrochloride(1:x)
• CAS NO: 42518-06-9
• Molecular Formula: C₆H₇N₃*ClH
• Molecular Weight: 157.6
• EINECS: 1312995-182-4
• Mol File: 42518-06-9.mol
• Article Data: 21

Chemical Properties

• Melting Point: 263 °C
• Boiling Point: 240.7°C at 760 mmHg
• Flash Point: 99.4°C
• Appearance: /
• Vapor Pressure: 0.0374mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 4-AMIDINOPYRIDINIUM CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMIDINOPYRIDINIUM CHLORIDE(42518-06-9)
• EPA Substance Registry System: 4-AMIDINOPYRIDINIUM CHLORIDE(42518-06-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 42518-06-9(Hazardous Substances Data)

Usage

Chemical Properties

White to light brown solid

InChI:InChI=1/C6H7N3/c7-6(8)5-1-3-9-4-2-5/h1-4H,(H3,7,8)/p+1

Upstream product

• 100-48-1 pyridine-4-carbonitrile 
• 1594-57-6 pyridine-4-carboxamidoxime 
• 12125-02-9 ammonium chloride 
• 41050-96-8 pyridine-4-methylimine acid ethyl ester 
• 60-29-7 diethyl ether 
• 35451-46-8 methyl pyridine-4-carboximidate 

Downstream Products

• 56406-44-1 4-oxo-2-pyridin-4-yl-3,4-dihydro-pyrimidine-5-carboxylic acid ethyl ester 
• 301846-35-5 Ethyl 5-Amino-4-(3-methoxyphenyl)-2-(4-pyridyl)-thieno[2,3-d]pyrimidine-6-carboxylate 
• 150728-08-8 5-(o-methoxyphenoxy)-4,6-dihydroxy-2-(pyridin-4-yl)-pyrimidine 
• 61310-39-2 6-amino-2-pyridin-4-yl-3H-pyrimidin-4-one 
• 958365-78-1 7-benzyl-2-pyrid-4-yl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one 
• 42518-09-2 2-methyl-4,6-di-(4-pyridyl)-1,3,5-triazine 
• 3599-62-0 2-methyl-4,6-diphenyl-1,3,5-triazine 

Relevant articles and documents

Synthesis and evaluation of 2-pyridinylpyrimidines as inhibitors of HIV-1 structural protein assembly

In an effort to identify an HIV-1 capsid assembly inhibitor with improved solubility and potency, we synthesized two series of pyrimidine analogues based on our earlier lead compound N-(4-(ethoxycarbonyl)phenyl)-2-(pyridine-4-yl)quinazoline-4-amine. In vitro binding experiments showed that our series of 2-pyridine-4-ylpyrimidines had IC50values higher than 28 μM. Our series of 2-pyridine-3-ylpyrimidines exhibited IC50values ranging from 3 to 60 μM. The congeners with a fluoro substituent introduced at the 4-N-phenyl moiety, along with a methyl at C-6, represent potent HIV capsid assembly inhibitors binding to the C-terminal domain of the capsid protein.

HERBICIDAL PYRIDINIUM COMPOUNDS

Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as a pesticides, especially as herbicides.

Preparation of amidines from amidoximes via transfer hydrogenation

Amidoximes are reduced into amidine using triethyl silane and PdCl 2 in acetic acid. Copyright