425392-46-7

Upstream product

• 59937-01-8 2-phenylthiazole-4-carboxylic acid ethyl ester 
• 2227-79-4 benzenecarbothioamide 
• 70-23-5 ethyl Bromopyruvate 
• 425392-44-5 2-bromo-5-chlorothiazole-4-carboxylic acid ethyl ester 
• 98-80-6 phenylboronic acid 

Downstream Products

• 161198-41-0 ethyl 2,5-diphenyl-4-thiazolecarboxylate 
• 130161-15-8 4-bromo-2,5-diphenylthiazole 
• 2104-11-2 2,4,5-triphenylthiazole 
• 425392-56-9 2,5-diphenylthiazole-4-carboxylic acid 
• 3704-40-3 2,5-diphenyl-1,3-thiazole 

Relevant academic research and scientific papers

IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION

The present invention provides thiazole compounds of Formula I wherein W, Y, R0, R2, R4, R5, R6, R7, X1, X2, X3 and X4 are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of platelet aggregation and thus can be used as medicaments for treating or preventing thromboembolic disorders.

THIAZOLE DERIVATIVES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS

The present invention relates to thiazole derivatives of Formula (I) and their use as P2Y12 receptor antagonists in the treatment and/or prevention of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular and of cere

Regiocontrolled Synthesis of Substituted Thiazoles

(Formula Presented) The regiocontrolled synthesis of 2,5-disubstituted and 2,4,5-trisubstituted thiazoles from ethyl 2-bromo-5-chloro-4-thiazolecarboxylate 1 using sequential palladium-catalyzed coupling reactions is described.