2104-11-2

Basic information

• Product Name: 2,4,5-TRIPHENYL-1,3-THIAZOLE
• Synonyms: 2,4,5-TRIPHENYL-1,3-THIAZOLE;2,4,5-TRIPHENYLTHIAZOLE
• CAS NO: 2104-11-2
• Molecular Formula: C₂₁H₁₅NS
• Molecular Weight: 313.42
• Mol File: 2104-11-2.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 470.4°Cat760mmHg
• Flash Point: 234.5°C
• Appearance: /
• Density: 1.169g/cm³
• Vapor Pressure: 1.43E-08mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: 2,4,5-TRIPHENYL-1,3-THIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,5-TRIPHENYL-1,3-THIAZOLE(2104-11-2)
• EPA Substance Registry System: 2,4,5-TRIPHENYL-1,3-THIAZOLE(2104-11-2)

Safety Data

• Hazardous Substances Data: 2104-11-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C21H15NS/c1-4-10-16(11-5-1)19-20(17-12-6-2-7-13-17)23-21(22-19)18-14-8-3-9-15-18/h1-15H

Upstream product

• 108-86-1 bromobenzene 
• 2227-79-4 benzenecarbothioamide 
• 501-65-5 diphenyl acetylene 
• 451-40-1 phenyl benzyl ketone 
• 100-52-7 benzaldehyde 
• 109028-02-6 α-benzoylmercapto-deoxybenzoin 
• 28170-13-0 thiobenzoic acid potassium salt 
• 1484-50-0 desyl bromide 
• 98-80-6 phenylboronic acid 
• 1826-12-6 4-phenyl-thiazole 
• 1826-13-7 5-phenylthiazole 
• 591-50-4 iodobenzene 
• 1826-11-5 2-phenylthiazole 
• 1826-15-9 4,5-diphenylthiazole 

Downstream Products

• 573-34-2 2,4,5-triphenyloxazole 

Relevant articles and documents

Diversity-Oriented Synthesis of α-Functionalized Acylborons and Borylated Heteroarenes by Nucleophilic Ring Opening of α-Chloroepoxyboronates

The ring-opening reactions of N-methyliminodiacetyl (MIDA) α-chloroepoxyboronates with different nucleophiles allow the modular synthesis of a diverse array of organoboronates. These include seven types of α-functionalized acylboronates and seven types of

Method for synthesizing thiazole heterocyclic compound through photocatalysis

The invention discloses a method for synthesizing a thiazole heterocyclic compound through photocatalysis. The method comprises the steps of adopting alkyne and thioamide as raw materials, irradiatingby a blue light lamp in the condition of air and room temperature under the catalysis of acridine salt, and stirring to obtain the thiazole heterocyclic compound. The raw materials used in method areeasy to obtain, and the adding of the transition metal and other oxidants is avoided, and the reaction can be initiated by only using the green and sustainable visible light; and the method is simpleand convenient to operate, considerable in yield, environment-friendly, and good in application prospect.

Exploration and Optimization of an Efficient One-pot Sequential Synthesis of Di/tri-substituted Thiazoles from α-Bromoketones, Thioacids Salt, and Ammonium Acetate

Exploration of scope of an optimized one-pot sequential procedure for preparing of 2,4-di- and 2,4,5-tri-substituted thiazoles has been accomplished. The synthesis was performed by the initial formation of a β-keto-thioester intermediate from nucleophilic substitution of α-bromoketones with thioacid potassium salts, followed by treatment with ammonium acetate and one equivalent of acetic acid in toluene to form imine intermediate eventually leading to cyclization yielding thiazoles. This procedure should be highlighted with a flexible way to control the substitution pattern around thiazole ring by choosing appropriately substituted α-bromoketones even containing acid labile functionality and thioacid potassium salts, and thus its applicability is very wide.