425398-91-0Relevant academic research and scientific papers
A versatile synthesis of pyrazolo[3,4-c]isoquinoline derivatives by reaction of 4-aryl-5-aminopyrazoles with aryl/heteroaryl aldehydes: The effect of the heterocycle on the reaction pathways
Bogza, Sergei L.,Kobrakov, Konstantin I.,Malienko, Anna A.,Perepichka, Igor F.,Sujkov, Sergei Yu.,Bryce, Martin R.,Lyubchik, Svetlana B.,Batsanov, Andrei S.,Bogdan, Natalya M.
, p. 932 - 940 (2007/10/03)
The reaction of 4-(3,4-dimethoxyphenyl)-5-aminopyrazoles 7A-D with aromatic and heterocyclic aldehydes in strong acidic media (trifluoroacetic or formic acid) has been studied. The initial azomethine derivatives 8 undergo cyclization similar to the Pictet
