425619-08-5Relevant academic research and scientific papers
Facile room-temperature assembly of the 1,2,4-oxadiazole core from readily available amidoximes and carboxylic acids
Sharonova, Tatyana,Pankrat'eva, Vitalina,Savko, Polyna,Baykov, Sergey,Shetnev, Anton
, p. 2824 - 2827 (2018/06/13)
A one-pot ambient-temperature procedure for the synthesis of 3,5-disubstituted-1,2,4-oxadiazoles from amidoximes and carboxylic acids under superbase-promoted conditions is reported.
Rapid multistep synthesis of 1,2,4-oxadiazoles in a single continuous microreactor sequence
Grant, Daniel,Dahl, Russell,Cosford, Nicholas D. P.
experimental part, p. 7219 - 7223 (2009/05/07)
(Chemical Equation Presented) A general method for the synthesis of bis-substituted 1,2,4-oxadiazoles from readily available arylnitriles and activated carbonyls in a single continuous microreactor sequence is described. The synthesis incorporates three s
