426836-32-0Relevant articles and documents
Asymmetric synthesis of both enantiomers of two acyclic nucleoside analogues related to d4T and acyclovir
Ewing, David F,Gla?on, Virginie,Mackenzie, Grahame,Len, Christophe
, p. 989 - 991 (2002)
The enantiomers of 1-{[(2-hydroxy-1-phenyl)ethoxy]methyl}thymine and 9-{[(2-hydroxy-1-phenyl)ethoxy]methyl}guanine have been obtained in high yield in five steps from (R)- and (S)-1-phenylethan-1,2-diol. These chiral compounds are acyclic nucleoside analo
Synthesis, conformation and antiviral activity of nucleoside analogues with the (2-hydroxy-1-phenylethoxy)methyl glycone - A family of nucleoside analogues related to d4T and aciclovir
Ewing, David F.,Glacon, Virginie,Len, Christophe,Mackenzie, Grahame
, p. 1461 - 1468 (2007/10/03)
A complete family of acyclic nucleoside analogues has been obtained by combining the (2-hydroxy-1-phenylethoxy)methyl glycone with the nucleoside bases adenine, guanine, cytosine, thymine and uracil. In each case both optical antipodes have been prepared