42747-54-6Relevant academic research and scientific papers
Synthesis and structure-activity relationships evaluation of benzothiazinone derivatives as potential anti-tubercular agents
Gao, Chao,Ye, Ting-Hong,Wang, Ning-Yu,Zeng, Xiu-Xiu,Zhang, Li-Dan,Xiong, Ying,You, Xin-Yu,Xia, Yong,Xu, Ying,Peng, Cui-Ting,Zuo, Wei-Qiong,Wei, Yuquan,Yu, Luo-Ting
supporting information, p. 4919 - 4922 (2013/09/02)
N-Alkyl and heterocycle substituted 1,3-benzothiazin-4-one (BTZ) derivatives were synthesized. The anti-mycobacterial activities of these compounds were evaluated by determination of minimal inhibitory concentration (MIC) for Mycobacterium tuberculosis H3
NOVEL NITROPHENYL MUSTARD AND NITROPHENYLAZIRIDINE ALCOHOLS AND THEIR CORRESPONDING PHOSPHATES AND THEIR USE AS TARGETED CYTOTOXIC AGENTS
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Page/Page column 27; 35-36, (2008/06/13)
The present invention relates to novel nitrophenyl mustard and nitrophenylaziridine alcohols, to their corresponding phosphates, to their use as targeted cytotoxic agents; as bioreductive drugs in hypoxic tumours, and to their use in cell ablation, includ
NITROANILINE-BASED ALKYLATING AGENTS AND THEIR USE AS PRODRUGS
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Page 13; 24-25, (2008/06/13)
Nitroaniline-based unsymmetrical mustards of the general formula (I) are provided, together with methods of preparation and methods for their use as produgs for gene-dependent enzyme prodrug therapy (GDEPT) and cell ablation therapy in conjuction with nit
Mustard prodrugs for activation by Escherichia coli nitroreductase in gene-directed enzyme prodrug therapy
Friedlos, Frank,Denny, William A.,Palmer, Brian D.,Springer, Caroline J.
, p. 1270 - 1275 (2007/10/03)
Twenty nitrogen mustard analogues derived from 5-(aziridin-l-yl)-2,4- dinitrobenzamide (CB 1954, 1) were evaluated as candidate prodrugs for gene- directed enzyme prodrug therapy (GDEPT) in Chinese hamster V79 cell lines engineered to express Escherichia
Hypoxia-selective antitumor agents. 14. Synthesis and hypoxic cell cytotoxicity of regioisomers of the hypoxia-selective cytotoxin 5-[N,N- bis(2-chloroethyl)amino]-2,4-dinitrobenzamide
Palmer,Wilson,Anderson,Boyd,Denny
, p. 2518 - 2528 (2007/10/03)
A series of regioisomers of the novel hypoxia-selective cytotoxin (HSC) 5- [N,N-bis(2-chloroethyl)amino]-2,4-dinitrobenzamide (2a) have been prepared by displacement of the chloro group from methyl chlorodinitrobenzoates or the corresponding carboxamides
Synthesis and Spectral Characterization of Blue Dyes of the Benzene Series
Thiel, W.,Mayer, R.,Jauer, E.-A.,Modrow, H.,Dost, H.
, p. 497 - 514 (2007/10/02)
53 Donor-acceptor substituted azo dyes of the benzene series were prepared by diazonium-coupling reactions (1a-s) or halogen-cyanide exchange (->2a-x, 3a-j).Described are the preparation of the amines 4a-m and the coupling compounds 5a-t and the procedure of diazotizing and coupling.The colouristic and spectroscopic data show that compounds of the general formula 1 are excellent brilliant blue azo dyes usefull for dyeing polyester material.
Cyano phenylene dioxamic molecules
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, (2008/06/13)
Compounds represented below SPC1 And pharmaceutical compositions thereof, the compositions including the non-substituted phenylene dioxamates are useful in the prophylactic treatment of sensitized mammals for allergy and all anaphylactic reactions of a reagin or non-reagin mediated nature.
