4278-80-2Relevant academic research and scientific papers
Amido pincer nickel catalyzed kumada cross-coupling of aryl, heteroaryl, and vinyl chlorides
Zhang, Xue-Qi,Wang, Zhong-Xia
supporting information, p. 2081 - 2084 (2013/10/21)
Amido pincer nickel complexes {Ni(Cl)[2-P(Ph2)C 6H4NC(Ph)=NAr]} (Ar = 4-MeC6H4, 1; Ar = 4-ClC6H4, 2; Ar = 4-MeOC6H4, 3) were shown to efficiently catalyze the cross-coupling of activated, unactivated, and deactivated aryl chlorides, N-heteroaryl chlorides, 1,4-dichlorobenzene, and vinyl chlorides with aryl Grignard reagents. Georg Thieme Verlag Stuttgart, New York.
Development of a polymer bound Wittig reaction and use in multi-step organic synthesis for the overall conversion of alcohols to β-hydroxyamines
Bolli, Martin H.,Ley, Steven V.
, p. 2243 - 2246 (2007/10/03)
An efficient combinatorial access to β-hydroxyamines suitable for automation is achieved by the mild oxidation of alcohols to aldehydes by polymer supported perruthenate (PSP), the subsequent clean olefination of the obtained aldehydes by polymer supported Wittig reagents followed by the epoxidation of the olefins by dimethyldioxirane (DMDO), and the final aminolysis of the epoxides with various amines is described.
