42789-13-9

Usage

Uses

Used in Pharmaceutical Industry:
1,2-Nonanediol is used as a chemical intermediate for the production of pharmaceuticals, contributing to the synthesis of various medicinal compounds.
Used in Plasticizer Production:
1,2-Nonanediol is used as a chemical intermediate in the production of plasticizers, which are additives that increase the flexibility and workability of plastics.
Used in Lubricant Industry:
1,2-Nonanediol is used as a chemical intermediate in the formulation of lubricants, enhancing their performance and reducing friction in various mechanical applications.
Used in Personal Care Products:
1,2-Nonanediol is used as a humectant and moisturizing agent in personal care products such as lotions and creams, helping to retain moisture and improve skin hydration.
Used as a Solvent:
1,2-Nonanediol can be used as a solvent in various chemical processes, facilitating the dissolution and interaction of different substances.
Used as a Chemical Precursor:
1,2-Nonanediol serves as a chemical precursor in the synthesis of other organic compounds, enabling the creation of a wide range of products.

InChI:InChI=1/C9H20O2/c1-2-3-4-5-6-7-9(11)8-10/h9-11H,2-8H2,1H3

Upstream product

• 124-13-0 Octanal 
• 122588-50-5 (dimethylisopropoxysilyl)methylmagnesium chloride 
• 94616-95-2 1-(Isopropoxy-dimethyl-silanyl)-nonan-2-ol 
• 124838-41-1 S-methyl 2-hydroxynonanethioate 
• 124-11-8 non-1-ene 
• 110-83-8 cyclohexene 
• 1433993-67-9 4-(hydroxymethyl)-1,3,2-dioxathiolane-2,2-dioxide 
• 44767-62-6 n-hexylmagnesium chloride 
• 28114-20-7 1,2-epoxynonane 
• 2404-44-6 1,2-Epoxydecane 
• 108952-47-2 4-hepta-2,4,6-triynyl-2,2-dimethyl-[1,3]dioxolane 
• 31502-14-4 2-nonenyl alcohol 
• 124838-33-1 1,1,1-tris(methylthio)-2-nonanol 
• 65311-41-3 1-hydroperoxy-nonan-2-ol 

Relevant academic research and scientific papers

Chemo- and Regioselective Functionalization of Polyols through Catalytic C(sp3)-C(sp3) Kumada-Type Coupling of Cyclic Sulfate Esters

This contribution describes a copper-catalyzed, C(sp3)-C(sp3) cross-coupling reaction of cyclic sulfate esters, a distinct class of electrophilic derivatives of polyols, with alkyl Grignard reagents to afford functionalized alcohol products in good yields. The method is operationally simple and highlights the potential of cyclic sulfate esters as highly reactive substrates in catalytic, chemoselective polyol transformations.

Formation of persulphate from sodium sulphite and molecular oxygen catalysed by H5PV2Mo10O40-aerobic epoxidation and hydrolysis

The H5PV2Mo10O40 polyoxometalate catalysed the electron transfer oxidation of sulphite to yield a sulphite radical, SO3- that upon addition of O2 yielded a peroxosulphate species efficient for the H5PV2Mo10O40 catalysed epoxidation of alkenes. The acidic polyoxometalate further catalysed hydrolysis of the epoxide to give vicinal diols in high yields. This journal is

Preparation of high purity 1,2-diols by catalytic oxidation of linear terminal alkenes with H2O2 in the presence of carboxylic acids under solvent-free conditions

The oxidation of terminal alkenes was smoothly catalyzed by a recyclable and environmentally friendly catalytic system: [(C18H 37)2N(CH3)2]3[PW 4O16]/H2O2/formic acid. This new catalytic system is not only capable of catalyzing oxidation of terminal alkenes with a phase-transfer character, but also under solvent-free conditions, avoiding the use of chlorinated solvents. Many different kinds of terminal alkenes could be converted to the corresponding 1,2-diols of high purity in high yields. The catalyst could be easily separated and reused after reaction. Both fresh and used [(C18H37)2N(CH3) 2]3[PW4O16] catalyst was characterized by Raman and FTIR.

Regioselective epoxidation of different types of double bonds over large-pore titanium silicate Ti-β

Regioselective epoxidation of different types of double bonds located within the cyclic and acyclic parts of bulky olefins has been investigated using large-pore titanium silicate Ti-β in the presence of dilute aqueous H 2O2 as oxidant under mild liquid-phase conditions. Our experimental results revealed that side-chain vinylic double bonds are selectively epoxidized than those in the cyclohexene-ring. The epoxidation tendency of various bulky olefins with different positional and/or geometric isomers over Ti-β follows the order: terminal -CC- > ring -CC- ≈ bicyclic ring -CC- > allylic C - H bond. Unlike 4-vinyl-1-cyclohexene, epoxidation of an equimolar mixture of cyclohexene and 1-hexene under identical conditions using Ti-β exhibits completely different selectivity and product distributions. Steric factor and accessibility of reactants to active Ti-sites are responsible for the observed regioselectivity of bulky alkenes.

DERMATOLOGICAL COMPOSITIONS AND METHODS

Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds, including alcohols, diols and/or triols and their analogues.

Treatment of neurodegenerative diseases

Disclosed are methods for increasing the differentiation of mammalian neuronal cells for purposes of treating neurodegenerative diseases or nerve damage by administration of various compounds including alcohols, diols and/or triols and their analogues.

Treatment of diseases mediated by the nitric oxide/cGMP/protein kinase G pathway

Disclosed are methods and compositions for stimulating cellular nitric oxide (NO) synthesis, cyclic guanosine monophosphate levels (cGMP), and protein kinase G (PKG) activity for purposes of treating diseases mediated by deficiencies in the NO/cGMP/PKG signal transduction pathway, by administration of various compounds including alcohols, diols and/or triols and their analogues.

Synthesis of S-Methyl 2-Hydrxyalkanethioates, 2-Hydroxyalkanoic Acids and Related Compounds via the Addition Reaction of Tris(methylthio)methanide Ion to Alkanals

In connection with the studies on biological activities on myrmicacin and related compounds, the synthetic method for 2-hydroxyalkanoic acids and the corresponding 1,2-diols was studied.The addition reaction of tris(methylthio)methyllithium to the aldehydes (propanal-dodecanal) gave the corresponding 1,1,-tris(methylthio)-2-alkanols 1a-j.Treatment of 1 with mercury(II) chloride-mercury(II) oxide in water-acetone afforded S-methyl 2-hydroxyalkanethioates 2a-j, and in methanol methyl 2-hydroxyalkanoates 3c-j were obtained.Reduction of the thioates 2 with lithium aluminium hydride gave 1,2-diols 4c-j and saponification produced the corresponding 2-hydroxyalkanoic acids 5c-j.

SILAFUNCTIONAL COMPOUNDS IN ORGANIC SYNTHESIS. 30. INTRAMOLECULAR HYDROSILATION OF ALKENYL ALCOHOLS: A NEW APPROACH TO THE REGIOSELECTIVE SYNTHESIS OF 1,2- AND 1,3-DIOLS

Intramolecular hydrosilation of allyl and homoallyl alcohols and the subsequent oxidative cleavage of the resultant carbon-silicon bond have provided a new approach to the regio-controlled synthesis of 1,2- and/or 1,3-diols.

SILAFUNCTIONAL COMPOUNDS IN ORGANIC SYNTHESIS. 27. (ISOPROPOXYDIMETHYLSILYL)METHYL GRIGNARD REAGENT: A NEW NUCLEOPHILIC HYDROXYMETHYLATING AGENT FOR ALDEHYDES AND KETONES

Nucleophilic hydroxymethylation of aldehydes and ketones has been achieved by the reaction with the (isopropoxydimethylsilyl)methyl Grignard reagent and the subsequent oxidative cleavage of the carbon-silicon bond.