42842-87-5

Upstream product

• 18269-31-3 Methyl α-(trimethylsilyl)acrylate 
• 100-52-7 benzaldehyde 
• 591-51-5 phenyllithium 
• 18020-59-2 methyl 3-hydroxy-2-methylidene-3-phenylpropionate 
• 71-43-2 benzene 
• 125151-82-8 methyl α-methylene-β-[(p-toluenesulfonyl)amino]-3-phenylpropionate 
• 98-80-6 phenylboronic acid 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 80-62-6 methacrylic acid methyl ester 
• 124957-36-4 Methyl 3-acetoxy-2-methylene-3-phenylpropanoate 
• 3958-47-2 triphenylindium 
• 98-88-4 benzoyl chloride 
• 780-69-8 triethoxyphenylsilane 

Downstream Products

• 874913-38-9 (Z)-2-(Methoxy-phenyl-methyl)-3-phenyl-acrylic acid methyl ester 
• 83303-55-3 1-Phenyl-1H-indene-2-carboxylic acid methyl ester 
• 56751-26-9 ethyl (E)-α-(diphenylmethyl)cinnamate 
• 56751-27-0 (Z)-methyl 2-benzhydryl-3-phenylacrylate 

Relevant academic research and scientific papers

Palladium-Catalyzed Cross-Coupling of Acetates of Baylis-Hillman Adducts and Potassium Organotrifluoroborates

(Matrix presented) The cross-coupling of potassium organotrifluoroborates and acetates of Baylis-Hillman adducts proceeds readily in moderate to excellent yield in the presence of Pd(OAc)2. The reaction tolerates hindered trifluoroborate salts,

The Friedel-Crafts reaction of the Baylis-Hillman adducts

A simple and convenient methodology for the stereoselective construction of 2-benzyl substituted trisubstituted olefins via sulfuric acid catalyzed Friedel-Crafts reaction of benzene with Baylis-Hillman adducts is described.

Intermolecular C-O addition of carboxylic acids to arynes: Synthesis of o-hydroxyaryl ketones, xanthones, 4-chromanones, and flavones

An efficient and simple route to biologically and pharmaceutically important o-hydroxyaryl ketones, xanthones, 4-chromanones, and flavones has been developed utilizing readily available carboxylic acids and commercially available o-(trimethylsilyl)aryl tr

Rhodium-catalyzed formation of stereocontrolled trisubstituted alkenes from Baylis-Hillman adducts

We report here efficient and general conditions for the formation of stereodefined trisubstituted alkenes using the rhodium-catalyzed reaction of unactivated Baylis-Hillman adducts with either organoboronic acids and potassium trifluoro(organo)borates. Th

Rhodium fluorapatite catalyst for the synthesis of trisubstituted olefins via cross coupling of Baylis-Hillman adducts and arylboronic acids

(Chemical Equation Presented) Treatment of fluorapatite (prepared by incorporating basic species F- in apatite in situ by coprecipitation) with an aqueous solution of RhCl3 resulted in rhodium-exchanged fluorapatite catalyst (RhFAP),

Chemo-, regio- and stereoselective addition of triorganoindium reagents to acetates of Baylis-Hillman adducts: a new strategy for the synthesis of (E)- and (Z)-trisubstituted alkenes

The addition of several trialkyl or triarylindium reagents to the acetates of Baylis-Hillman adducts proceeds readily under the catalysis of copper and palladium derivatives. The reactions of trialkylindiums are catalyzed efficiently by CuI whereas additi

Access to stereodefined trisubstituted alkenes via rhodium-catalyzed 1,4-addition of potassium trifluoro(organo)borates to Baylis-Hillman adducts

In the presence of a rhodium catalyst, unactivated Baylis-Hillman adducts reacted regioselectively with potassium trifluoro(organo)borates to afford stereodefined trisubstituted alkenes with good yields. This highly efficient reaction (aerobic conditions,

Montmorillonite K10 clay-catalyzed synthesis of substituted 1-aryl indenes from Baylis-Hillman adducts

An eco-friend method for the synthesis of 1-aryl indenes from Baylis-Hillman adducts using Mont. K10 and microwave combination as catalyst system and a procedure for the synthesis of β-phenyl-substituted-protected Baylis-Hillman adducts with highly Z-sele

Palladium-catalyzed cross-coupling of Baylis-Hillman acetate adducts with organosilanes

A cross-coupling reaction between acetates of Baylis-Hillman adducts and organosilanes is described. A nonconventional solvent poly(ethylene glycol) (PEG) is used as the reaction medium.

Friedel-Crafts reaction of the Baylis-Hillman adducts of N-tosylimine derivatives

Friedel-Crafts reaction of aromatic compounds with the Baylis-Hillman adducts of N-tosylimine derivatives in the presence of sulfuric acid provided a stereoselective methodology for the preparation of 2-benzylsubstituted olefins in moderate yields.