428499-81-4Relevant articles and documents
Synthesis of an α-aminophosphonate nucleoside as an inhibitor of S-adenosyl-L-homocysteine hydrolase
Steere, Jennifer A.,Sampson, Peter B.,Honek, John F.
, p. 457 - 460 (2007/10/03)
A phosphonic acid analogue of S-adenosyl-L-homocysteine was prepared by a novel method and the epimeric mixture separated. Preliminary studies indicate that each epimer causes time-dependent inactivation of S-adenosyl-L-homocysteine hydrolase, however each presented distinct kinetic characteristics.