80993-30-2

Upstream product

• 762-04-9 phosphonic acid diethyl ester 
• 80993-23-3 Benzhydryl-methylene-amine 
• 91-00-9 Benzhydrylamine 
• 91290-81-2 1,3,5-tris(diphenylmethyl)-hexahydro-1,3,5-triazine 

Downstream Products

• 776-74-9 Bromodiphenylmethane 
• 428499-81-4 [3-[(3aS,4S,6R,6aR)-6-(6-Amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethylsulfanyl]-1-(benzhydrylidene-amino)-propyl]-phosphonic acid diethyl ester 
• 428499-80-3 [1-(benzhydrylidene-amino)-3-bromo-propyl]-phosphonic acid diethyl ester 
• 122570-91-6 diethyl N-(diphenylmethylene) aminomethyl phosphonate 

Relevant academic research and scientific papers

Synthesis of an α-aminophosphonate nucleoside as an inhibitor of S-adenosyl-L-homocysteine hydrolase

A phosphonic acid analogue of S-adenosyl-L-homocysteine was prepared by a novel method and the epimeric mixture separated. Preliminary studies indicate that each epimer causes time-dependent inactivation of S-adenosyl-L-homocysteine hydrolase, however each presented distinct kinetic characteristics.

Synthesis of 1-Aminoalkane Phosphonic Acids via Benzhydrylic Schiff Bases

A simple synthesis of 1-aminoalkanephosphonic acids is described.The addition of diethylphosphite to alkylidene- and arylidenebenzhydrylamines yields the N-benzhydryl-1-aminoalkanephosphonic acid esters.The title compounds are formed by treatment of the N-blocked esters with hydrobromic acid.The starting amine can be recycled from the hydrylbromide. - Key words: 1-Aminoalkane Phosphonic Acids, Benzhydrylic, Schiff Bases