42933-07-3

Basic information

• Product Name: METHYL 3-BROMO-2-OXO-2H-PYRAN-5-CARBOXYLATE
• Synonyms: METHYL 3-BROMO-2-OXO-2H-PYRAN-5-CARBOXYLATE;methyl 5-bromo-6-oxopyran-3-carboxylate
• CAS NO: 42933-07-3
• Molecular Formula: C₇H₅BrO₄
• Molecular Weight: 233.02
• Product Categories: Esters;Ring Systems
• Mol File: 42933-07-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 285.4±40.0 °C(Predicted)
• Appearance: /
• Density: 1.812±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: METHYL 3-BROMO-2-OXO-2H-PYRAN-5-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3-BROMO-2-OXO-2H-PYRAN-5-CARBOXYLATE(42933-07-3)
• EPA Substance Registry System: METHYL 3-BROMO-2-OXO-2H-PYRAN-5-CARBOXYLATE(42933-07-3)

Safety Data

• Hazardous Substances Data: 42933-07-3(Hazardous Substances Data)

Usage

General Description

Methyl 3-Bromo-2-oxo-2H-pyran-5-carboxylate is a chemical compound with the molecular formula C7H5BrO4. It is a derivative of pyran, containing a bromo and a carboxylate group. METHYL 3-BROMO-2-OXO-2H-PYRAN-5-CARBOXYLATE is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is also known for its role in organic chemistry reactions, where it acts as a reagent in the formation of various other chemical compounds. Methyl 3-Bromo-2-oxo-2H-pyran-5-carboxylate is a versatile compound with a wide range of applications in the chemical and pharmaceutical industries.

Upstream product

• 500-05-0 2H-pyran-2-one-5-carboxylic acid 
• 67-56-1 methanol 
• 6018-41-3 methyl coumalate 

Downstream Products

• 5043-29-8 methyl 1-bromo-3-naphthoate 

Relevant articles and documents

[4+2] Cycloadditions between 2-pyrones and benzyne. Application to the synthesis of binaphthyls

Cycloaddition of benzyne to 2-pyrones affords the corresponding naphthalene derivatives, the intermediate bicyclic adduct not being detected. Benzopyrones do not react with benzyne under similar conditions probably because this would require the fused aromatic ring to lose aromaticity in the Diels-Alder transition state, which is therefore destabilized. 4-Bromo-2-naphthoic acid methyl ester (obtained by cycloaddition of benzyne to 3-bromo-5-carboxymethylpyran-2-one) can be transformed into 3,3'-dicarboxymethyl-1,1'-binaphthyl by Ni-mediated dimerization.

HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS

The invention relates to heterocyclic compounds and their use as antibiotics and/or as antibiotic potentiators. The compounds may act as colistin potentiators and SOS inhibitors.

A PROCESS FOR THE PREPARATION OF 3-CYANO-1-NAPHTHOIC ACID AND SOME ANALOGUES THEREOF

The present invention is related to a process for the preparation of 3-cyano-1-naphthoic acid and some analogues thereof of formula (1), the intermediate 1-halo-3-cyano naphthalene and some analogues thereof used in this process and a process for the preparation of said intermediate.