4300-35-0

Basic information

• Product Name: 1-(2-nitrophenyl)-3-phenylurea
• Synonyms: 1-(2-nitrophenyl)-3-phenylurea
• CAS NO: 4300-35-0
• Molecular Weight: 257.249
• Mol File: 4300-35-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1-(2-nitrophenyl)-3-phenylurea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-nitrophenyl)-3-phenylurea(4300-35-0)
• EPA Substance Registry System: 1-(2-nitrophenyl)-3-phenylurea(4300-35-0)

Safety Data

• Hazardous Substances Data: 4300-35-0(Hazardous Substances Data)

Usage

Chemical class

Phenylurea

Physical state

White crystalline solid

Function

Herbicide and plant growth regulator

Mode of action

Inhibits photosynthesis in plants

Target organisms

Grasses, broadleaf weeds, and sedges

Applications

Agricultural and horticultural uses, non-crop areas (industrial sites, rights-of-way, aquatic environments)

Toxicity

Moderately toxic to humans

Handling

Should be handled with caution

Upstream product

• 3320-86-3 2-nitrophenyl isocyanate 
• 62-53-3 aniline 
• 108-88-3 toluene 
• 71-43-2 benzene 
• 3493-72-9 N-(2-nitro-phenyl)-benzimidoyl chloride 
• 59387-72-3 N-(2-nitro-phenyl)-benzamide oxime 
• 201230-82-2 carbon monoxide 
• 98-95-3 nitrobenzene 
• 88-74-4 2-nitro-aniline 
• 103-71-9 phenyl isocyanate 
• 63451-02-5 (2-nitro-phenyl)-carbamoyl chloride 
• 13725-30-9 methyl N-(2-nitrophenyl)carbamate 
• 610-14-0 2-nitrobenzyl chloride 
• 552-16-9 ortho-nitrobenzoic acid 

Downstream Products

• 93-98-1 N-phenyl benzoyl amide 

Relevant articles and documents

Ortho-substituent effects on diphenylurea packing motifs

Hydrogen bonding between urea groups is a widely used motif in crystal engineering and supramolecular chemistry studies. In an effort to discern how the steric and electronic properties of substituents affect the molecular conformation and crystal packing

Polystyrene anchored ruthenium(II) complex catalyzed carbonylation of nitrobenzene and amines for the synthesis of disubstituted ureas

The catalytically active complex [Ru(PS-imd)(CO)2Cl2] (PS-imd = polystyrene anchored imidazole) was synthesized and characterized using various spectroscopic techniques. The complex is well characterized and highly stable. The catalytic activity of the resulting species was investigated towards the synthesis of diphenyl urea and other disubstituted ureas. The experiments were carried out under high CO pressure, high temperature condition in mild coordinating media. The catalyst was found to produce excellent yields with high product selectivity. Variable yields are obtained depending on the substituent on nitrobenzene and aniline. The effects of co-solvent and co-catalyst were also studied. The catalyst was very stable and could be reused for more than five times without any noticeable loss of its catalytic activity.

Friedel-Crafts-type reactions with ureas and thioureas

Despite the relatively low reactivities of urea and thiourea functional groups towards nucleophilic attack, we have found conditions in which they are useful substrates in Friedel-Crafts reactions. The Bronsted superacid, triflic acid, promotes these reactions and a mechanism is proposed involving dicationic, superelectrophilic intermediates.